Preparation and characterization of anodized titanium surfaces and their effect on osteoblast responses.
Preparation and characterization of anodized titanium surfaces and their effect on osteoblast responses.
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阳极氧化钛表面的制备和表征及其对成骨细胞反应的影响。
DOI：
10.1563/741.1
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
J. Ong
中科院分区：
文献类型：
--
作者：
K. Kim;T. Kwon;Shin‐Yoon Kim;I. Kang;Sukyoung Kim;Y. Yang;J. Ong
在这项研究中，钛（Ti）的表面改性与β-甘油磷酸钠和醋酸钙（Ca）的混合物的阳极氧化，并通过扫描电子显微镜，X射线衍射和电子探针显微分析的阳极氧化表面进行了表征。还评价了体外成骨细胞对阳极氧化的反应。观察到产生的阳极氧化物具有互连的孔（直径为0.5-2微米）和中等粗糙度（0.60-1.00微米）。此外，观察到阳极氧化物具有无定形和无定形氧化物。在阳极氧化过程中，钙和磷离子沉积在钛氧化物上。成骨细胞的分化，如碱性磷酸酶的生产，阳极氧化表面上得到加强。因此，从这项研究中得出结论，磷酸钙可以通过阳极氧化沉积在钛表面上。还得出结论，成骨细胞的表型表达通过磷酸钙的存在和阳极氧化钛表面上的更高粗糙度而增强。
In this study, titanium (Ti) surface was modified by anodizing with a mixture of beta-glycerophosphate sodium and calcium (Ca) acetate, and the anodized surfaces were characterized by scanning electron microscopy, X-ray diffraction, and electron probe microanalysis. In vitro osteoblast response to anodized oxide was also evaluated. The anodic oxide produced was observed to have interconnected pores (0.5-2 microm in diameter) and intermediate roughness (0.60-1.00 microm). In addition, anodic oxide was observed to have amorphous and anatase oxide. Calcium and phosphorus ions were deposited on the Ti oxide during anodization. Osteoblast differentiation, as indicated by alkaline phosphatase production, was enhanced on anodized surfaces. It was thus concluded from this study that Ca phosphate can be deposited on Ti surfaces by anodization. It was also concluded that the phenotypic expression of osteoblast was enhanced by the presence of Ca phosphate and higher roughness on anodized Ti surfaces.
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DOI：
10.1002/jbm.a.10578
发表时间：
2003-10
期刊：
Journal of biomedical materials research. Part A
影响因子：
--
作者：
Y. Yang;R. Cavin;J. Ong
通讯作者：
Y. Yang;R. Cavin;J. Ong
影响因子：
14
作者：
S. A. Bender;J. Bumgardner;Roach;K. Bessho;J. Ong
通讯作者：
S. A. Bender;J. Bumgardner;Roach;K. Bessho;J. Ong
影响因子：
14
作者：
Boyan, BD;Hummert, TW;Schwartz, Z
通讯作者：
Schwartz, Z
体外在钛表面培养的成骨细胞增强细胞外基质的产生和矿化。
影响因子：
4
作者：
Groessner-Schreiber,B;Tuan,RS
通讯作者：
Tuan,RS