Impact of pediatric obesity on acute asthma exacerbation in Japan
Impact of pediatric obesity on acute asthma exacerbation in Japan
复制标题
日本儿童肥胖对哮喘急性发作的影响
DOI：
10.1111/pai.12801
复制
发表时间：
2017
影响因子：
4.4
通讯作者：
Yasunaga Hideo
中科院分区：
文献类型：
--
作者：
Okubo Yusuke;Michihata Nobuaki;Yoshida Koichi;Morisaki Naho;Matsui Hiroki;Fushimi Kiyohide;Yasunaga Hideo
背景哮喘和肥胖是儿童常见的健康问题。本研究调查肥胖对哮喘急性加重期住院儿童的影响。方法利用日本国家住院病人数据库，获取3~8岁哮喘患儿的出院记录。根据世界卫生组织提供的身高体重和年龄体重指数将患者分为体重不足组、正常体重组、超重组和肥胖组。结果共鉴定出38例679例患者，其中体重不足3177例，正常体重28例，正常体重28例，超重3334例，肥胖3264例。肥胖组再入院30天(调整后优势比1.26；95%可信区间1.03-1.54)和住院时间(调整后差异0.12天；95%可信区间0.10-0.20天)明显高于正常体重组。阈值是体重的第91个百分位数的长度或身体质量指数与30天再次入院的关系。结论肥胖是儿童哮喘反复入院的危险因素，对儿童肥胖的预防具有重要意义。
BackgroundAsthma and obesity are common health problems in children. This study investigated the impact of obesity on children hospitalized with acute asthma exacerbation.MethodsWe obtained the hospital discharge records of inpatients aged 3‐8 years with a diagnosis of asthma using a national inpatient database in Japan. The patients were classified into underweight, normal weight, overweight, and obese groups using weight for height and body mass index for age provided by the World Health Organization. We compared 30‐day re‐admission, need for intensive care, mean total hospitalization costs, and length of hospital stay between the 4 groups using multivariable regression models.ResultsOverall, 38 679 patients were identified, including 3177 underweight, 28 904 normal weight, 3334 overweight, and 3264 obese patients. The obese group showed significantly higher 30‐day re‐admission (adjusted odds ratio, 1.26; 95% confidence interval, 1.03‐1.54) and longer length of stay (adjusted difference, 0.12 days; 95% confidence interval, 0.10‐0.20 days) than the normal weight group. The threshold was a 91st percentile of weight for length or body mass index for the relationship with 30‐day re‐admission. No significant difference was observed between the 4 groups regarding the need for intensive care and total hospitalization costs.ConclusionThese findings demonstrated that obesity was a risk factor for repeated admissions caused by asthma in children, indicating the importance for the prevention of pediatric obesity.
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DOI：
10.1111/pai.12804
发表时间：
2017-12
期刊：
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
影响因子：
--
作者：
Namara B;Nash S;Lule SA;Akurut H;Mpairwe H;Akello F;Tumusiime J;Kizza M;Kabagenyi J;Nkurunungi G;Muhangi L;Webb EL;Muwanga M;Elliott AM
通讯作者：
Elliott AM
肥胖的年轻哮喘患者气道阻塞会恶化。
DOI：
10.1016/j.jaip.2015.05.009
发表时间：
2015
期刊：
The journal of allergy and clinical immunology. In practice
影响因子：
--
作者：
Strunk,RobertC;Colvin,Ryan;Bacharier,LeonardB;Fuhlbrigge,Anne;Forno,Erick;Arbelaez,AnaMaria;Tantisira,KelanG;ChildhoodAsthmaManagementProgramResearchGroup
通讯作者：
ChildhoodAsthmaManagementProgramResearchGroup
体重指数和小儿哮喘结果
影响因子：
1.4
作者：
J. Hom;E. Morley;P. Sasso;R. Sinert
通讯作者：
R. Sinert
女性因哮喘住院比例较高的相关因素：FRIAM 研究
影响因子：
8
作者：
Carlos Melero Moreno;A. López;Mercedes García;Carolina Cisneros Serrano;Javier Jareño Esteban;Maria Teresa Ramirez Prieto
通讯作者：
Maria Teresa Ramirez Prieto
DOI：
10.1164/rccm.201211-2116oc
发表时间：
2013-04-01
影响因子：
24.7
作者：
Borrell, Luisa N.;Nguyen, Elizabeth A.;Burchard, Esteban G.
通讯作者：
Burchard, Esteban G.