Connectivity adaptations in dopaminergic systems define the brain maturity of investors.

Connectivity adaptations in dopaminergic systems define the brain maturity of investors.
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DOI:
10.1038/s41598-021-91227-x
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发表时间:
2021-06-03
期刊:
影响因子:
4.6
通讯作者:
Ortiz T
Ortiz T
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Ortiz-Teran E;Diez I;Sepulcre J;Lopez-Pascual J;Ortiz T

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投资决策依赖于对外部刺激的感知,沿着而来的是对大脑-身体信号的整合,所有这些都是由经验塑造的。由于经验能够塑造人类大脑的结构和功能,我们使用了一种新的神经影像学连接组学遗传方法来研究投资工作经验对大脑解剖结构的影响。我们发现,资深投资者在多巴胺相关通路中显示出更高的灰质体积和更高的结构性大脑连接,以及一组与肾上腺素和去甲肾上腺素生物合成(SLC 6A 3,TH和SLC 18 A2)功能相关的基因,这些基因似乎参与了金融交易期间的奖励处理和身体压力反应。这些结果表明,随着投资成熟度的提高,老年投资者在控制自己的情绪同时提高身体意识的过程中,儿茶酚胺发挥了关键作用。
Investment decisions rely on perceptions from external stimuli along with the integration of inner brain-body signals, all of which are shaped by experience. As experience is capable of molding both the structure and function of the human brain, we have used a novel neuroimaging connectomic-genetic approach to investigate the influence of investment work experience on brain anatomy. We found that senior investors display higher gray matter volume and increased structural brain connectivity in dopamine-related pathways, as well as a set of genes functionally associated with adrenaline and noradrenaline biosynthesis (SLC6A3, TH and SLC18A2), which is seemingly involved in reward processing and bodily stress responses during financial trading. These results suggest the key role of catecholamines in the way senior investors harness their emotions while raising bodily awareness as they grow in investment maturity.
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