Alcohol consumption and non-communicable diseases: epidemiology and policy implications.
Alcohol consumption and non-communicable diseases: epidemiology and policy implications.
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DOI：
10.1111/j.1360-0443.2011.03605.x
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发表时间：
2011-10
期刊：
影响因子：
--
通讯作者：
Rehm J
中科院分区：
文献类型：
--
作者：
Parry CD;Patra J;Rehm J
本文总结了不同的饮酒模式与不同的非传染性疾病（NCD）结果之间的关系，并估计了饮酒对全球死亡率和疾病负担的总体影响。基于已发表的饮酒与疾病关系的荟萃分析的叙述性评论，以及对应用于全球疾病负担研究最新修订版的比较风险评估估计的检查。酒精与八种不同的癌症存在因果关系（在不同程度上），且风险随着饮酒量的增加而增加。同样，饮酒与许多心血管结局有害，包括高血压、出血性中风和心房颤动。对于其他心血管结局，关系更为复杂。此外，酒精还与各种形式的肝脏疾病（特别是脂肪肝、酒精性肝炎和肝硬化）和胰腺炎有关。对于糖尿病来说，这种关系也很复杂。保守估计，全球非传染性疾病相关死亡负担、净损失生命年 (YLL) 和净残疾调整生命年 (DALY) 分别有 3.4%、5.0% 和 2.4% 归因于饮酒，其中癌症和肝硬化的负担尤其高。这种负担在前苏联国家尤其明显。酒精与非传染性疾病，特别是癌症、心血管疾病、肝脏疾病、胰腺炎和糖尿病之间存在密切联系，这些研究结果支持世卫组织呼吁实施循证策略，减少有害使用酒精。
This paper summarises the relationships between different patterns of alcohol consumption and various on non-communicable disease (NCD) outcomes and estimates the overall impact of alcohol consumption on global mortality and burden of disease. A narrative review, based on published meta-analyses of alcohol consumption-disease relations, together with an examination of the Comparative Risk Assessment estimates applied to the latest available revision of Global Burden of Disease study. Alcohol is causally linked (to varying degrees) to eight different cancers, with the risk increasing with the volume consumed. Similarly alcohol use is detrimentally related to many cardiovascular outcomes, including hypertension, haemorrhagic stroke and atrial fibrillation. For other cardiovascular outcomes the relationship is more complex. Alcohol is furthermore linked to various forms of liver disease (particularly with fatty liver, alcoholic hepatitis and cirrhosis) and pancreatitis. For diabetes the relationship is also complex. Conservatively of the global NCD-related burden of deaths, net years of life lost (YLL) and net disability adjusted life years (DALYs), 3.4%, 5.0% and 2.4% respectively can be attributed to alcohol consumption, with the burden being particularly high for cancer and liver cirrhosis. This burden is especially pronounced in countries of the former Soviet Union. There is a strong link between alcohol and NCDs, particularly cancer, cardiovascular disease, liver disease, pancreatitis and diabetes and these findings support calls by WHO to implement evidence-based strategies to reduce harmful use of alcohol.
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影响因子：
4.5
作者：
Patra J;Taylor B;Irving H;Roerecke M;Baliunas D;Mohapatra S;Rehm J
通讯作者：
Rehm J
影响因子：
3.9
作者：
Rehm, J;Room, R;Jernigan, D
通讯作者：
Jernigan, D
影响因子：
3.1
作者：
Rehm, Juergen;Klotsche, Jens;Patra, Jayadeep
通讯作者：
Patra, Jayadeep
影响因子：
6
作者：
Gmel, Gerhard;Kuntsche, Emmanuel;Rehm, Juergen
通讯作者：
Rehm, Juergen
影响因子：
168.9
作者：
Beaglehole, Robert;Bonita, Ruth;Watt, Judith
通讯作者：
Watt, Judith