Nuclear and genome dynamics in multinucleate ascomycete fungi.
Nuclear and genome dynamics in multinucleate ascomycete fungi.
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DOI：
10.1016/j.cub.2011.06.042
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发表时间：
2011-09-27
期刊：
影响因子：
--
通讯作者：
Glass NL
中科院分区：
文献类型：
--
作者：
Roper M;Ellison C;Taylor JW;Glass NL
个体之间的遗传变异对进化和适应至关重要。然而，器官内的遗传变异也塑造了许多生物的生活史，包括丝状真菌。单个真菌合胞体可以含有数千或数百万个移动的且可能具有不同基因型的细胞核，每个细胞核都具有再生新生物体的能力。由于无性或有性孢子的传播会在许多这些物种中繁殖单个细胞核，因此在细胞核水平上发挥作用的选择创造了竞争和合作基因组动态的潜力。最近在粗糙脉孢菌和核盘菌中的工作阐明了核种群如何协调真菌生长和其他行为，并揭示了预防和监管基因组间冲突的分子和物理机制。最近的结果，从人口水平的基因组研究在各种丝状真菌表明，菌丝体之间的核交换和异源核之间的重组可能是更重要的真菌进化，多样性和新的毒力菌株的出现比以前已经认识到。
Genetic variation between individuals is essential to evolution and adaptation. However, intra-organismic genetic variation also shapes the life histories of many organisms, including filamentous fungi. A single fungal syncytium can harbor thousands or millions of mobile and potentially genotypically different nuclei, each having the capacity to regenerate a new organism. Because the dispersal of asexual or sexual spores propagates individual nuclei in many of these species, selection acting at the level of nuclei creates the potential for competitive and cooperative genome dynamics. Recent work in Neurospora crassa and Sclerotinia sclerotiorum has illuminated how nuclear populations are coordinated for fungal growth and other behaviors and has revealed both molecular and physical mechanisms for preventing and policing inter-genomic conflict. Recent results from population-level genomic studies in a variety of filamentous fungi suggest that nuclear exchange between mycelia and recombination between heterospecific nuclei may be of more importance to fungal evolution, diversity and the emergence of newly virulent strains than has previously been recognized.
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DOI：
10.1073/pnas.2533483100
发表时间：
2003-12-23
影响因子：
11.1
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
1.5
作者：
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通讯作者：
ROPER, JA
DOI：
10.1098/rspb.2002.2148
发表时间：
2002-11-07
影响因子：
4.7
作者：
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通讯作者：
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