Effect of changing instilled volume for bronchoalveolar lavage in patients with interstitial lung disease.

Effect of changing instilled volume for bronchoalveolar lavage in patients with interstitial lung disease.
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改变输注量对间质性肺疾病患者支气管肺泡灌洗的影响。

DOI:
10.1164/arrd.1985.132.2.390
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发表时间:
1985
期刊:
The American review of respiratory disease
影响因子:
--
通讯作者:
Baughman,RP
Baughman,RP
中科院分区:
--
文献类型:
--
作者:
Dohn,MN;Baughman,RP

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患有或不患有间质性肺疾病 (ILD) 的患者均接受 4 次 60 ml 生理盐水的支气管肺泡灌洗 (BAL)。每次推注后抽出液体,合并第一次和第二次推注后的结果并与第三次和第四次推注后的结果进行比较。在对照组(n=9)中,上半场后淋巴细胞和中性粒细胞的百分比显着高于下半场(上半场:淋巴细胞,8 ± 1.9%,平均值±SEM;中性粒细胞,2 ± 1.2%。下半场:淋巴细胞,5 ± 1.2%(p < 0.01);中性粒细胞,0.3 ± 0.12%(p <在 ILD 组 (n=8) 中,淋巴细胞数量从 15 ± 4.9% 增加到 20 ± 3.9% (p < 0.05),中性粒细胞数量从 8 ± 4.8% 增加到 10 ± 5.6%。当使用较大体积时,BAL 液细胞群的异常更加明显。
Patients with and without interstitial lung disease (ILD) underwent bronchoalveolar lavage (BAL) with 4 boluses of 60 ml of normal saline. Fluid was withdrawn after each bolus, and the results after the first and second bolus were pooled and compared with the results after the third and fourth bolus. In the control group (n=9), there was a significantly higher percentage of lymphocytes and neutrophils after the first half than after the second half (first half: lymphocytes, 8 ± 1.9%, mean ± SEM; neutrophils, 2 ± 1.2%. Second half: lymphocytes, 5 ± 1.2% (p < 0.01); neutrophils, 0.3 ± 0.12% (p < 0.05). In the ILD group (n=8), there was a rise in the number of lymphocytes from 15 ± 4.9% to 20 ± 3.9% (p < 0.05) and the number of neutrophils from 8 ± 4.8% to 10 ± 5.6%. The ILD group had more cells aspirated after the second half than after the first half of the BAL, whereas the control group did not. Abnormalities in the cell population of the BAL fluid were more striking when the larger volume was used.
来自正常人肺下呼吸道的免疫活性细胞。
DOI: --
发表时间: 1975
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