The effect of pre-transplant pain and chronic disease self-efficacy on quality of life domains in the year following hematopoietic stem cell transplantation.
The effect of pre-transplant pain and chronic disease self-efficacy on quality of life domains in the year following hematopoietic stem cell transplantation.
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DOI：
10.1007/s00520-017-3947-6
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发表时间：
2018-04
期刊：
影响因子：
--
通讯作者：
Somers TJ
中科院分区：
文献类型：
--
作者：
O'Sullivan ML;Shelby RA;Dorfman CS;Kelleher SA;Fisher HM;Rowe Nichols KA;Keefe FJ;Sung AD;Somers TJ
疼痛对于造血干细胞移植（HSCT）患者是常见的，并且可能在移植前、移植后急性地以及移植后数月或数年经历。持续疼痛的HSCT患者可能存在移植后生活质量差的风险;然而，移植前疼痛对移植后生活质量的影响尚不清楚。慢性病管理的自我效能与癌症患者的生活质量相关，并可能影响HSCT患者的生活质量。主要目的是检查移植前疼痛和自我效能对移植后一年生活质量的影响。166名HSCT患者完成了问卷调查，提供了移植前、出院时和移植后3个月、6个月和12个月的疼痛、自我效能和生活质量信息，作为纵向观察性研究的一部分。线性混合模型检查了这些变量的轨迹以及移植前疼痛和自我效能对移植后生活质量的影响。疼痛和社会和情感生活质量在移植后一年保持稳定，而自我效能和身体和功能生活质量得到改善。移植前疼痛与移植后较低的身体健康显着相关。移植前自我效能较低与移植后所有领域的生活质量较低有关。除了移植前疼痛的影响之外，管理慢性疾病的自我效能对于理解移植后的生活质量非常重要。在移植前识别疼痛和/或自我效能低的患者可能允许使用自我管理策略进行早期干预。
Pain is common for hematopoietic stem cell transplant (HSCT) patients, and may be experienced pre-transplant, acutely post-transplant, and for months or years following transplant. HSCT patients with persistent pain may be at risk for poor quality of life following transplant; however, the impact of pre-transplant pain on quality of life post-transplant is not well understood. Self-efficacy for chronic disease management is associated with quality of life among cancer patients and may impact quality of life for HSCT patients. The primary aim was to examine the effect of pre-transplant pain and self-efficacy on quality of life domains in the year following transplant. 166 HSCT patients completed questionnaires providing information on pain, self-efficacy, and quality of life prior to transplant, at discharge, and 3-, 6-, and 12-months post-transplant as part of a longitudinal, observational study. Linear mixed modeling examined the trajectories of these variables and the effect of pre-transplant pain and self-efficacy on post-transplant quality of life. Pain and social and emotional quality of life remained stable in the year following transplant while self-efficacy and physical and functional quality of life improved. Pre-transplant pain was significantly related to lower physical well-being post-transplant. Lower pre-transplant self-efficacy was related to lower quality of life across all domains post-transplant. Above and beyond the effect of pre-transplant pain, self-efficacy for managing chronic disease is important in understanding quality of life following transplant. Identifying patients with pain and/or low self-efficacy pre-transplant may allow for early intervention with self-management strategies.
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影响因子：
3.1
作者：
Kopp, M;Schweigkofler, H;Sperner-Unterwerger, B
通讯作者：
Sperner-Unterwerger, B
DOI：
10.1182/asheducation-2010.1.248
发表时间：
2010-12-01
影响因子：
3
作者：
Bevans, Margaret
通讯作者：
Bevans, Margaret
影响因子：
2.1
作者：
Hochhausen, Nicole;Altmaier, Elizabeth M.;Henslee-Downey, Jean
通讯作者：
Henslee-Downey, Jean
影响因子：
3.1
作者：
Mols, Floortje;Oerlemans, Simone;van de Poll-Franse, Lonneke V.
通讯作者：
van de Poll-Franse, Lonneke V.
影响因子：
4.8
作者：
McQuellon, RP;Russell, GB;Hurd, DD
通讯作者：
Hurd, DD