Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness.
Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness.
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DOI：
10.1177/0269881111420188
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发表时间：
2011-11
期刊：
影响因子：
--
通讯作者：
Griffiths RR
中科院分区：
文献类型：
--
作者：
MacLean KA;Johnson MW;Griffiths RR
大量的证据，包括对人格变化的纵向分析，表明核心人格特质在30岁以后主要是稳定的。据我们所知，没有研究表明，在实验操纵的离散事件后，健康成年人的个性发生了变化。有趣的是，双盲对照研究表明，经典的致幻剂psilocybin会带来个人和精神上重要的神秘体验，这些体验可以预测行为，态度和价值观的长期变化。在本报告中，我们评估了裸盖菇素对人格的五个广泛领域-神经质，外向性，开放性，可接受性和尽责性变化的影响。与参与者声称的致幻剂刺激的审美欣赏，想象力和创造力的增加相一致，我们发现高剂量裸盖菇素治疗后开放性显着增加。在psilocybin会议期间有神秘经历的参与者中，开放性在会议后一年多仍显着高于基线。研究结果表明，裸盖菇素和神秘类型的经验在成年人的性格变化中发挥着特定的作用。
A large body of evidence, including longitudinal analyses of personality change, suggests that core personality traits are predominantly stable after age 30. To our knowledge, no study has demonstrated changes in personality in healthy adults after an experimentally manipulated discrete event. Intriguingly, double-blind controlled studies have shown that the classic hallucinogen psilocybin occasions personally and spiritually significant mystical experiences that predict long-term changes in behaviors, attitudes and values. In the present report we assessed the effect of psilocybin on changes in the five broad domains of personality - Neuroticism, Extroversion, Openness, Agreeableness, and Conscientiousness. Consistent with participant claims of hallucinogen-occasioned increases in aesthetic appreciation, imagination, and creativity, we found significant increases in Openness following a high-dose psilocybin session. In participants who had mystical experiences during their psilocybin session, Openness remained significantly higher than baseline more than one year after the session. The findings suggest a specific role for psilocybin and mystical-type experiences in adult personality change.
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影响因子：
6.6
作者：
Costa, PT;Bagby, RM;McCrae, RR
通讯作者：
McCrae, RR
DOI：
10.1177/0269881108093587
发表时间：
2008-08
期刊：
Journal of psychopharmacology (Oxford, England)
影响因子：
--
作者：
Johnson M;Richards W;Griffiths R
通讯作者：
Griffiths R
影响因子：
4.3
作者：
Dittrich, A
通讯作者：
Dittrich, A
影响因子：
7
作者：
MacCallum, RC;Zhang, SB;Rucker, DD
通讯作者：
Rucker, DD
影响因子：
1.9
作者：
Grob, CS;McKenna, DJ;Boone, KB
通讯作者：
Boone, KB