Modifiable and non-modifiable epidemiological risk factors for acne, acne severity and acne scarring among Malaysian Chinese: a cross-sectional study.
Modifiable and non-modifiable epidemiological risk factors for acne, acne severity and acne scarring among Malaysian Chinese: a cross-sectional study.
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DOI：
10.1186/s12889-021-10681-4
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发表时间：
2021-03-27
影响因子：
4.5
通讯作者：
Chew FT
中科院分区：
文献类型：
--
作者：
Say YH;Heng AHS;Reginald K;Wong YR;Teh KF;Rawanan Shah SM;Sio YY;Ng YT;Matta SA;Pang SL;Chew FT
寻常痤疮是一种非常普遍的多因素炎症性皮肤病，可根据病变的类型、数量和严重程度分为不同的严重程度和疤痕等级。虽然许多流行病学研究调查了痤疮表现的危险因素，但很少有研究专门研究痤疮严重程度和疤痕的危险因素。因此，本研究调查了马来西亚华人的痤疮患病率、痤疮严重程度和疤痕等级，以及它们相关的不可改变和可改变的流行病学危险因素。作为横断面研究的一部分，共有1840名受试者（1117例/723例对照）完成了一份调查问卷，包括社会人口统计学、家族史、生活方式因素、饮食习惯和痤疮史。由训练有素的人员进一步评估痤疮病例的严重程度（n = 1051）和疤痕（n = 1052）等级。大多数痤疮病例（高达69%）为轻度痤疮或1/2级瘢痕，21.6%为中度/重度痤疮，5.5%为3/4级瘢痕。男性出现痤疮疤痕的风险明显更高。那些患有痤疮的人，无论其严重程度和疤痕等级如何，都有很强的阳性家族史（父母和/或兄弟姐妹）。经常食用（大部分或全天）早餐时经常食用的食物（黄油、益生菌饮料、谷物和牛奶）可降低痤疮出现和痤疮疤痕的风险，而定期食用（每周一次/两次）坚果和汉堡/快餐可降低痤疮严重程度的风险。饮酒会显著增加患痤疮的风险，而父亲、父母和家人吸烟则会降低患更严重痤疮的风险。总之，阳性家族史是影响痤疮表现、严重程度和瘢痕形成的重要因素。经常食用通常在早餐期间食用的食物可以预防痤疮的出现。在线版本包含补充材料，可在10.1186/s12889-021-10681-4获得。
Acne vulgaris, a highly prevalent multifactorial inflammatory skin disease, can be categorised into different severity and scarring grades based on the type, number, and severity of lesions. While many epidemiology studies have investigated the risk factors for acne presentation, fewer studies have specifically studied the risk factors for acne severity and scarring. Therefore, this study investigated the prevalence of acne, acne severity and scarring grades, and their associated non-modifiable and modifiable epidemiological risk factors among Malaysian Chinese. A total of 1840 subjects (1117 cases/723 controls) completed an investigator-administered questionnaire as part of a cross-sectional study, which include socio-demographics, familial history, lifestyle factors, dietary habits, and acne history. Acne cases were further evaluated for their severity (n = 1051) and scarring (n = 1052) grades by a trained personnel. Majority of the acne cases (up to 69%) had mild acne or Grade 1/2 scarring, while 21.6% had moderate/severe acne and 5.5% had Grade 3/4 scarring. Males had significantly higher risk of presenting with higher grades of acne scarring. Those who had acne, regardless of severity and scarring grades, had strong positive familial history (either in parents and/or sibling). Frequent consumption (most or all days) of foods that are commonly consumed during breakfast (butter, probiotic drinks, cereals and milk) decreased the risk for acne presentation and higher acne scarring, while periodic consumption (once/twice per week) of nuts and burgers/fast food decreased the risk for higher acne severity. Alcohol drinking was significantly associated with increased risk for acne presentation, while paternal, parental and household smoking were associated with reduced risk of more severe acne. In conclusion, positive familial history is a strong predisposing factor in influencing acne presentation, severity and scarring. Frequent consumption of foods that are commonly consumed during breakfast is protective against acne presentation. The online version contains supplementary material available at 10.1186/s12889-021-10681-4.
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影响因子：
4.1
作者：
MOTLEY, RJ;FINLAY, AY
通讯作者：
FINLAY, AY
影响因子：
13.8
作者：
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通讯作者：
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DOI：
10.1111/j.1468-3083.2011.04329.x
发表时间：
2012-12-01
影响因子：
9.2
作者：
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通讯作者：
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1.2
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影响因子：
4.6
作者：
Heng, Anna Hwee Sing;Chew, Fook Tim
通讯作者：
Chew, Fook Tim