Biologic Potential of Calcium Phosphate Biopowders Produced via Decomposition Combustion Synthesis.

Biologic Potential of Calcium Phosphate Biopowders Produced via Decomposition Combustion Synthesis.
复制标题

DOI:
10.1016/j.ceramint.2015.02.105
复制
发表时间:
2015-07-01
影响因子:
5.2
通讯作者:
Ayers R
Ayers R
中科院分区:
材料科学1区
文献类型:
--
作者:
Vollmer N;King KB;Ayers R

文献摘要

参考文献

被引文献

相似文献

本研究的目的是评估一种新的反应合成系统生产的磷酸钙(CaP)生物粉的生物潜力。分解燃烧合成(DCS)是一种改进的燃烧合成方法,能够生产用于骨组织工程应用的CaP粉末。在DCS期间,调节反应物盐与燃料的化学计量比以改变产物化学和形态。利用体外试验方法确定控制产品组成对细胞毒性、增殖、生物相容性和生物矿化的影响。在体外,与CaP粉末一起培养的人胎儿成骨细胞(ATCC,CRL-11372)显示出扁平的形态,并且均匀地包围CaP颗粒。成骨细胞出芽形成含钙、磷的基质囊泡。通过DCS生产的CaP粉末是具有生物活性的合成骨移植替代材料的来源
The aim of this research was to evaluate the biologic potential of calcium phosphate (CaP) biopowders produced with a novel reaction synthesis system. Decomposition combustion synthesis (DCS) is a modified combustion synthesis method capable of producing CaP powders for use in bone tissue engineering applications. During DCS, the stoichiometric ratio of reactant salt to fuel was adjusted to alter product chemistry and morphology. In vitro testing methods were utilized to determine the effects of controlling product composition on cytotoxicity, proliferation, biocompatibility and biomineralization. In vitro, human fetal osteoblasts (ATCC, CRL-11372) cultured with CaP powder displayed a flattened morphology, and uniformly encompassed the CaP particulates. Matrix vesicles containing calcium and phosphorous budded from the osteoblast cells. CaP powders produced via DCS are a source of biologically active, synthetic, bone graft substitute materials
DOI: 10.1002/jbm.a.31017
发表时间: 2007-06-01
影响因子: 4.9
作者:
Ayers, Reed A.;Burkes, Douglas E.;Moore, John J.
通讯作者: Moore, John J.
DOI: 10.1016/j.matbio.2005.11.001
发表时间: 2006-04-01
期刊: MATRIX BIOLOGY
影响因子: 6.9
作者:
Al-Jallad, HF;Nakano, Y;Kaartinen, MT
通讯作者: Kaartinen, MT
DOI: 10.1016/j.biomaterials.2005.01.025
发表时间: 2005-08-01
期刊: BIOMATERIALS
影响因子: 14
作者:
Declerq, HA;Verbeeck, RMH;Cornelissen, MJ
通讯作者: Cornelissen, MJ
DOI: 10.1016/s0142-9612(02)00411-8
发表时间: 2003-02-01
期刊: BIOMATERIALS
影响因子: 14
作者:
Ehara, A;Ogata, K;Umakoshi, Y
通讯作者: Umakoshi, Y
DOI: 10.1016/j.msec.2005.08.028
发表时间: 2006-09-01
期刊: MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
影响因子: --
作者:
Ayers, Reed;Nielsen-Preiss, Sheila;Kleebe, Hans-Joachim
通讯作者: Kleebe, Hans-Joachim