A proposal for quality standards for measuring medication adherence in research.

A proposal for quality standards for measuring medication adherence in research.
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DOI:
10.1007/s10461-012-0172-7
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发表时间:
2013-01
期刊:
影响因子:
4.4
通讯作者:
Womack, Julie A.
Womack, Julie A.
中科院分区:
医学2区
文献类型:
--
作者:
Williams, Ann Bartley;Amico, K. Rivet;Bova, Carol;Womack, Julie A.

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在广泛认识到坚持药物治疗方案是抗逆转录病毒(ARV)有效性的关键十年后,关于坚持测量的“金标准”仍然存在相当大的争议。每种依从性测量方法都有优点和缺点,每种方法都依赖于特定的假设。关于依从性测量的假设范围和实施每种方法的多样性强烈表明,在使用特定测量的背景(例如,研究的操作方案)之外对特定测量进行评价可能导致对研究结果不应有的信心或缺乏信心。本文的目的是在常用的测量方法中提出一套最佳实践。关于什么信息应包括在已发表的报告中,就如何衡量坚持提供了建议,以促进改善在研究中的药物依从性的测量质量。
A decade after widespread recognition that adherence to medication regimens is key to antiretroviral (ARV) effectiveness, considerable controversy remains regarding a “gold standard” for adherence measurement. Each adherence measurement approach has strengths and weaknesses and each rests on specific assumptions. The range of assumptions regarding adherence measurement and the diversity with which each approach is implemented strongly suggest that the evaluation of a particular measure outside of the context in which it was used (e.g. the study’s operational protocol) may result in undeserved confidence or lack of confidence in study results. The purpose of this paper is to propose a set of best practices across commonly used measurement methods. Recommendations regarding what information should be included in published reports regarding how adherence was measured are provided to promote improvement in the quality of measurement of medication adherence in research.
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