Global Perspective of the Vitamin D Status of African-Caribbean Populations: A Systematic Review and Meta-analysis.

Global Perspective of the Vitamin D Status of African-Caribbean Populations: A Systematic Review and Meta-analysis.
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DOI:
10.1038/s41430-021-00980-9
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发表时间:
2022-04
影响因子:
4.7
通讯作者:
Lanham-New SA
Lanham-New SA
中科院分区:
医学3区
文献类型:
--
作者:
Vearing RM;Hart KH;Darling AL;Probst Y;Olayinka AS;Mendis J;Ribeiro H;Thakur S;Mendes M;Charlton K;Lanham-New SA

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维生素D缺乏仍然是一个全球性的公共卫生问题,特别是在少数民族群体中。本综述调查了全球非洲-加勒比人口的维生素D状况(通过25(OH)D和饮食摄入量测量)。从成立到2019年10月,通过检索关键数据库(PUBMED, Web of Science, Scopus)进行了系统评价。搜索词包括“维生素D状况”和“非洲-加勒比”。随机效应和固定效应荟萃分析采用均值和均值标准误差相结合的方法。这项研究产生了19篇论文,其中包括来自6个国家的5670名非洲裔加勒比人。一项荟萃分析发现,这一人群的25(OH)D水平在67.8 nmol/L时足够(bbb50 nmol/L), 95% CI(57.9, 7.6),但饮食中维生素D摄入量不足,仅为3.0微克/天,95% CI(1.67,4.31)。对于那些生活在低纬度地区的人来说,25(OH)D水平“不足”(根据研究作者的定义)仅在2型糖尿病患者和接受血液透析的患者中被发现。在高纬度地区的所有研究中都报告了膳食维生素D摄入量(根据英国推荐的营养摄入量为10微克/天)不理想。在建议膳食摄入量较低(加勒比地区建议膳食摄入量:每天2.5微克)的低纬度地区进行的研究发现,三分之二的研究发现摄入量“足够”。在低纬度地区的非洲-加勒比人口中发现25(OH)D充足。然而,在高纬度地区,25(OH)D缺乏和低膳食维生素D摄入量普遍存在。
Vitamin D deficiency remains a global public health issue, particularly in minority ethnic groups. This review investigates the vitamin D status (as measured by 25(OH)D and dietary intake) of the African-Caribbean population globally. A systematic review was conducted by searching key databases (PUBMED, Web of Science, Scopus) from inception until October 2019. Search terms included ‘Vitamin D status’ and ‘African-Caribbean’. A random effects and fixed effects meta-analysis was performed by combining means and standard error of the mean. The search yielded 19 papers that included n = 5670 African-Caribbean participants from six countries. A meta-analysis found this population to have sufficient (>50 nmol/L) 25(OH)D levels at 67.8 nmol/L, 95% CI (57.9, 7.6) but poor dietary intake of vitamin D at only 3.0 µg/day, 95% CI (1.67,4.31). For those living at low latitudes ‘insufficient’ (as defined by study authors) 25(OH)D levels were found only in participants with type 2 diabetes and in those undergoing haemodialysis. Suboptimal dietary vitamin D intake (according to the UK recommended nutrient intake of 10 µg/day) was reported in all studies at high latitudes. Studies at lower latitudes, with lower recommended dietary intakes (Caribbean recommended dietary intake: 2.5 µg/day) found ‘sufficient’ intake in two out of three studies. 25(OH)D sufficiency was found in African-Caribbean populations at lower latitudes. However, at higher latitudes, 25(OH)D deficiency and low dietary vitamin D intake was prevalent.
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