Microbiota's role in health and diseases.

Microbiota's role in health and diseases.
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DOI:
10.1007/s11356-021-14593-z
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发表时间:
2021-07
期刊:
Environmental science and pollution research international
影响因子:
--
通讯作者:
Kamel M
Kamel M
中科院分区:
其他
文献类型:
--
作者:
El-Sayed A;Aleya L;Kamel M

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微生物组是一个术语,通常是指栖息/生活在人类/动物体内或皮肤上的各种微生物的群落。它形成了一个复杂的生态系统,包括数万亿的细菌,共生体,甚至病原微生物。外部环境、饮食和生活方式是影响微生物组组成和活力的主要决定因素。最近的研究表明微生物组对健康和疾病的巨大影响。它们的数量、构成、变化和生存能力是动态的。所有这些因素都是许多健康疾病的诱发、发展和治疗的原因。严重的疾病,如癌症,代谢紊乱,心血管疾病,甚至精神分裂症等心理障碍都直接或间接地受到微生物群的影响。此外,在过去的几周里,关于COVID-19和微生物群之间联系的积累数据被公布。在本研究中,讨论了微生物组在健康和疾病中的作用。深入了解微生物群在疾病诱导中的确切作用,可以通过纠正饮食和生活方式来预防疾病,并为大多数疾病开发新的治疗概念。本综述汇集了来自最新研究的证据,并讨论了管理COVID-19大流行的建议营养方法。
The microbiome is a term that usually refers to the community of various microorganisms that inhabit/live inside human/animal bodies or on their skin. It forms a complex ecosystem that includes trillions of commensals, symbiotics, and even pathogenic microorganisms. The external environment, diet, and lifestyle are the major determinants influencing the microbiome’s composition and vitality. Recent studies have indicated the tremendous influence of the microbiome on health and disease. Their number, constitution, variation, and viability are dynamic. All these elements are responsible for the induction, development, and treatment of many health disorders. Serious diseases such as cancer, metabolic disorders, cardiovascular diseases, and even psychological disorders such as schizophrenia are influenced directly or indirectly by microbiota. In addition, in the last few weeks, accumulating data about the link between COVID-19 and the microbiota were published. In the present work, the role of the microbiome in health and disease is discussed. A deep understanding of the exact role of microbiota in disease induction enables the prevention of diseases and the development of new therapeutic concepts for most diseases through the correction of diet and lifestyle. The present review brings together evidence from the most recent works and discusses suggested nutraceutical approaches for the management of COVID-19 pandemic.
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