Inhibitory effects of Cyrtomium fortunei J. Smith root extract on melanogenesis.
Inhibitory effects of Cyrtomium fortunei J. Smith root extract on melanogenesis.
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DOI：
10.4103/0973-1296.113272
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发表时间：
2013-07
影响因子：
0.7
通讯作者：
Choi SY
中科院分区：
文献类型：
--
作者：
Choi SY
最近，大量的注意力已经指向来自天然产品的粗提取物用于化妆品应用的用途。因此，我们进行了一系列的实验，以研究皮肤脱色的性质的粗提取物，是来自传统的韩国药用植物。本研究对贯众的脱色作用进行了研究。通过评估其酪氨酸酶抑制作用、在melan-a细胞中的黑色素产生抑制特性和在棕色豚鼠皮肤中的脱色能力来评价贯众（Cyrtomium fortunei J. Smith）提取物的根对黑色素产生的抑制作用。贯众根的甲醇提取物似乎抑制酪氨酸酶活性和黑色素产生在黑色素-a细胞。此外，该提取物对紫外线诱导的棕色豚鼠皮肤色素沉着过度表现出脱色能力。这些结果表明，贯众的根可能被证明是有用的，在治疗皮肤色素沉着过度与过度的阳光照射。
Recently, a great deal of attention has been directed toward the use of crude extracts from natural products for cosmetic applications. Thus, we performed a series of experiments to investigate skin depigmenting properties of a crude extract that was derived from a traditional Korean medicinal plant. In this study, the depigmentational potency of Cyrtomium fortunei J. Smith was investigated. The inhibitory effects of the root of Cyrtomium fortunei J. Smith extract on melanin production were evaluated by assessing its tyrosinase inhibitory effects, melanin production-inhibitory properties in melan-a cells and depigmenting ability in brown guinea pig skin. The methanolic extract of the root of Cyrtomium fortunei J. Smith appeared to inhibit tyrosinase activity and melanin production in melan-a cells. In addition, this extract exhibited depigmenting ability on Ultra violet-induced hyper pigmentation in brown guinea pig skin. These results suggested that root of Cyrtomium fortunei J. Smith might prove useful in treating skin hyperpigmentation associated with excess sun-exposure.
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影响因子：
6.5
作者：
Fuller, BB;Drake, MA;Chaudhry, F
通讯作者：
Chaudhry, F
影响因子：
1.7
作者：
Koketsu, M;Choi, SY;Kim, SY
通讯作者：
Kim, SY
影响因子：
4.3
作者：
Guo, Jin-Peng;Pang, Ji;Li, Jun-Wen
通讯作者：
Li, Jun-Wen
影响因子：
4.3
作者：
Park, Keun-Tae;Kim, Jeong-Keun;Lim, Young-Hee
通讯作者：
Lim, Young-Hee
影响因子：
3
作者：
IMOKAWA, G;KAWAI, M;MOTEGI, I
通讯作者：
MOTEGI, I