Resting-state spontaneous fluctuations in brain activity: a new paradigm for presurgical planning using fMRI.
Resting-state spontaneous fluctuations in brain activity: a new paradigm for presurgical planning using fMRI.
复制标题
大脑活动的静息态自发波动:使用功能磁共振成像进行术前计划的新范例。
DOI:
10.1016/j.acra.2009.02.001
复制
发表时间:
2009-05
影响因子:
4.8
通讯作者:
Leuthardt, Eric C.
中科院分区:
文献类型:
--
作者:
Shimony, Joshua S.;Zhang, Dongyang;Johnston, James M.;Fox, Michael D.;Roy, Abhik;Leuthardt, Eric C.
Task evoked functional MRI (fMRI) has been used successfully in the study of brain function and clinically for pre-surgical localization of eloquent brain regions prior to the performance of brain surgery. This method requires patient cooperation and is not useful in patients with cognitive dysfunction or physical impairment. An alternative method that can overcome some of these disadvantages measures the intrinsic function of the brain using resting state fMRI. This method does not require any task performance and measures the spontaneous low frequency (<0.1 Hz) fluctuations of the fMRI signal over time. Resting state fMRI data can provide valuable pre-surgical information in many patients who cannot benefit from traditional task based fMRI. Our objective in the current review is to provide preliminary information, including advantages and remaining challenges, on the clinical utility of this technique for improving pre-surgical planning and individualized patient centered care.
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DOI:
10.1073/pnas.0504136102
发表时间:
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影响因子:
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通讯作者:
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