Monoclonal antibodies specific for members of the genus Endotrypanum.
Monoclonal antibodies specific for members of the genus Endotrypanum.
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对内锥虫属成员具有特异性的单克隆抗体。
DOI:
10.1111/j.1550-7408.1989.tb05526.x
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发表时间:
1989
期刊:
影响因子:
--
通讯作者:
McMahon-Pratt,D
中科院分区:
文献类型:
--
作者:
Lopes,AH;McMahon-Pratt,D
Twenty‐six monoclonal antibodies were produced against membrane‐enriched preparationsof Endotrypanum schaudinniorEndotrypanumsp. promastigotes. Fifteen of these monoclonal antibodies (E1‐E15) reacted only with the standard strain ofE. schaudinni, M6159. Monoclonal antibodies E16‐E26 were consideredEndotrypanumspecific; no cross reactivity was detected with any other genus of the family Trypanosomatidae(Leishmania, Trypanosoma, Leptomonas. HerpetomonasorCrithidia)by dot‐blot radioimmune assay. By indirect immunofluorescence assay, the antigens recognized byEndotrypanumspecific monoclonal antibodies appear to be associated with the surface of the parasite. Based on Western blot analysis, 4 antigenic molecules ranging in molecular weight from 24 kD to 160 kD were identified by monoclonal antibodies specific for the strain ofE. schaudinni, M6159. Monoclonal antibodies specific for the genusEndotrypanumidentified an antigen of molecular weight 48 kD as well as a diffuse component migrating with an apparent molecular weight of 64–200 kD.
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影响因子:
4.4
作者:
D. Mcmahon;E. Bennett;J. David
通讯作者:
J. David
影响因子:
3.1
作者:
P. Gardiner;C. Jaffe;D. Dwyer
通讯作者:
D. Dwyer
影响因子:
2.1
作者:
H. A. Christensen;A. Herrer
通讯作者:
A. Herrer
DOI:
--
发表时间:
1956
期刊:
影响因子:
--
作者:
F. Montero
通讯作者:
F. Montero
DOI:
10.1002/j.1460-2075.1984.tb02130.x
发表时间:
1984
期刊:
The EMBO journal
影响因子:
--
作者:
Handman,E;Greenblatt,CL;Goding,JW
通讯作者:
Goding,JW