ChromDB: the chromatin database.

ChromDB: the chromatin database.
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DOI:
10.1093/nar/gkm768
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Napoli C
Napoli C
中科院分区:
生物学2区
文献类型:
--
作者:
Gendler K;Paulsen T;Napoli C

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ChromDB网站(www.chromdb.org)展示了广泛生物体的染色质相关蛋白,包括RNAi相关蛋白。我们的主要重点是展示一组高度策划的植物基因,预测编码与染色质重塑相关的蛋白质。我们的目的是使这种集中策划的序列信息提供给研究和教学界,以支持比较分析,了解植物中的染色质蛋白质组,特别是在重要的作物物种,如玉米和水稻。模型动物和真菌蛋白质包括在数据库中,以促进染色质蛋白质组的完整的比较分析,并使数据库适用于所有染色质研究人员和教育工作者。染色质生物学和染色质重塑是涉及众多蛋白质的复杂过程,所述蛋白质调节染色质结构的动态变化,所述动态变化抑制或激活转录。我们努力以一种直接和比较的方式组织ChromDB数据,以帮助用户了解将DNA包装到染色质中所涉及的蛋白质的互补性。
The ChromDB website (http://www.chromdb.org) displays chromatin-associated proteins, including RNAi-associated proteins, for a broad range of organisms. Our primary focus is to display sets of highly curated plant genes predicted to encode proteins associated with chromatin remodeling. Our intent is to make this intensively curated sequence information available to the research and teaching communities in support of comparative analyses toward understanding the chromatin proteome in plants, especially in important crop species such as corn and rice. Model animal and fungal proteins are included in the database to facilitate a complete, comparative analysis of the chromatin proteome and to make the database applicable to all chromatin researchers and educators. Chromatin biology and chromatin remodeling are complex processes involving a multitude of proteins that regulate the dynamic changes in chromatin structure which either repress or activate transcription. We strive to organize ChromDB data in a straightforward and comparative manner to help users understand the complement of proteins involved in packaging DNA into chromatin.
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期刊: SCIENCE
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