Female Adult Aedes albopictus Suppression by Wolbachia-Infected Male Mosquitoes.
Female Adult Aedes albopictus Suppression by Wolbachia-Infected Male Mosquitoes.
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DOI：
10.1038/srep33846
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发表时间：
2016-09-23
影响因子：
4.6
通讯作者：
Dobson SL
中科院分区：
文献类型：
--
作者：
Mains JW;Brelsfoard CL;Rose RI;Dobson SL
登革热、基孔肯雅和寨卡病毒是具有越来越大的全球影响的病原体。在缺乏经批准的疫苗或治疗方法的情况下，他们的管理依赖于控制蚊子媒介。但传统的控制措施是不够的，白纹伊蚊(亚洲虎蚊)等入侵物种的范围正在扩大。转基因蚊子正在接受测试，但在一些国家，转基因蚊子的使用遇到了监管障碍和公众反对。沃尔巴克氏菌可以导致一种条件不孕症，这可以提供一种替代基因改造或辐射的方法。然而，目前尚不清楚是否公开释放、人工感染的雄性Ae。白纹伊蚊可以竞争性地交配和使雌性绝育，其水平足以抑制野外种群。此外，沃尔巴克氏菌在引种地点的意外建立可能是水平传播或无意中雌性释放的结果。2014年，美国环保局颁发的实验使用许可证批准了在美国肯塔基州列克星敦进行的试点实地试验。在这里，我们提供的数据显示，卵孵化和成年雌性数量的局部性减少。在田间没有观察到人工沃尔巴克氏菌类型的存在。文中还讨论了沃尔巴克氏菌感染雄虫作为生物杀虫剂来抑制Ae野外种群的应用。白纹伊蚊。
Dengue, chikungunya and zika viruses are pathogens with an increasing global impact. In the absence of an approved vaccine or therapy, their management relies on controlling the mosquito vectors. But traditional controls are inadequate, and the range of invasive species such as Aedes albopictus (Asian Tiger Mosquito) is expanding. Genetically modified mosquitoes are being tested, but their use has encountered regulatory barriers and public opposition in some countries. Wolbachia bacteria can cause a form of conditional sterility, which can provide an alternative to genetic modification or irradiation. It is unknown however, whether openly released, artificially infected male Ae. albopictus can competitively mate and sterilize females at a level adequate to suppress a field population. Also, the unintended establishment of Wolbachia at the introduction site could result from horizontal transmission or inadvertent female release. In 2014, an Experimental Use Permit from the United States Environmental Protection Agency approved a pilot field trial in Lexington, Kentucky, USA. Here, we present data showing localized reduction of both egg hatch and adult female numbers. The artificial Wolbachia type was not observed to establish in the field. The results are discussed in relation to the applied use of Wolbachia-infected males as a biopesticide to suppress field populations of Ae. albopictus.
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影响因子：
3.8
作者：
Carvalho DO;McKemey AR;Garziera L;Lacroix R;Donnelly CA;Alphey L;Malavasi A;Capurro ML
通讯作者：
Capurro ML
影响因子：
2.1
作者：
Bellini, Romeo;Albieri, Alessandro;Maini, Stefano
通讯作者：
Maini, Stefano
影响因子：
2.1
作者：
Calvitti, Maurizio;Moretti, Riccardo;Dobson, Stephen L.
通讯作者：
Dobson, Stephen L.
影响因子：
56.9
作者：
Xi, ZY;Khoo, CCH;Dobson, SL
通讯作者：
Dobson, SL
DOI：
10.1098/rspb.2000.1139
发表时间：
2000-07-07
影响因子：
4.7
作者：
Werren, JH;Windsor, DM
通讯作者：
Windsor, DM