Workshop: tuning the 'cough center'.
Workshop: tuning the 'cough center'.
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DOI：
10.1016/j.pupt.2010.12.010
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发表时间：
2011-06
影响因子：
3.2
通讯作者：
Other participants
中科院分区：
文献类型：
--
作者：
Widdicombe J;Tatar M;Fontana G;Hanacek J;Davenport P;Lavorini F;Bolser D;Other participants
研讨会讨论了“咳嗽中心”可以通过各种传入输入进行调节的机制。特别介绍了来自鼻、口、呼吸道和肺、大脑皮层、躯体组织和咽部的输入的影响。在所有这些部位中，来自肺部的咳嗽可以增加或减少其强度或改变其模式。因此，咳嗽的“调谐”可能是由于传入输入的相互作用，或者是脑干神经通路的敏化或脱敏。反应模式取决于正在研究的咳嗽的“类型”，在某些情况下，还取决于感觉输入脑干的时间。咳嗽输入也可能影响大脑的各种“非咳嗽”运动输出，尽管这不是研讨会的主要主题。主要结论是咳嗽不是延髓“咳嗽中心”的刻板印象输出，而是其模式和强度依赖于作用于“咳嗽中心”的许多传入输入。
The Workshop considered the mechanisms whereby the ‘cough center’ could be tuned by various afferent inputs. There were particular presentations on the effects of inputs from the nose, mouth, respiratory tract and lungs, cerebral cortex, somatic tissues and the pharynx. From all these sites cough induced from the lungs could be increased or decreased in its strength or modified in its pattern. Thus ‘tuning’ of cough could be due to the interaction of afferent inputs, or to the sensitization or desensitization of brainstem neural pathways. The pattern of response depended on the ‘type’ of cough being studied and, in some instances, on the timing of the sensory input into the brainstem. Cough inputs could also affect various ‘non-cough’ motor outputs from the brain, although this was not the main theme of the Workshop. The main conclusion was that cough is not a stereotyped output from the medullary ‘cough center’, but that its pattern and strength depend on many afferent inputs acting on the ‘cough center’.
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影响因子：
6
作者：
DIMITRIADOU, V;ROULEAU, A;GARBARG, M
通讯作者：
GARBARG, M
影响因子：
3.2
作者：
Gracely, Richard H.;Undem, Bradley J.;Banzett, Robert B.
通讯作者：
Banzett, Robert B.
影响因子：
2.3
作者：
Fontana, Giovanni A.;Lavorini, Federico
通讯作者：
Lavorini, Federico
影响因子：
2.3
作者：
Bolser, Donald C.;Poliacek, Ivan;Davenport, Paul W.
通讯作者：
Davenport, Paul W.
影响因子：
3.2
作者：
Dicpinigaitis, PV
通讯作者：
Dicpinigaitis, PV