Recent advances in Brucella abortus vaccines.

Recent advances in Brucella abortus vaccines.
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DOI:
10.1186/s13567-015-0199-7
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发表时间:
2015-07-08
影响因子:
4.4
通讯作者:
Lage AP
Lage AP
中科院分区:
农林科学2区
文献类型:
--
作者:
Dorneles EM;Sriranganathan N;Lage AP

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牛布氏杆菌疫苗在牛布氏杆菌病控制/根除计划中发挥着核心作用,并已在全球范围内成功使用了数十年。菌株19和RB 51是获批的B。牛流产疫苗株最常用于保护牛免受感染和流产。然而,由于这些疫苗显示出的一些缺点,已经进行了许多努力来开发新的疫苗,更安全和更有效,也可以用于其他易感动物物种。本文综述了近年来布鲁氏菌病疫苗的主要应用及新型B疫苗的研究进展。流产疫苗。
Brucella abortus vaccines play a central role in bovine brucellosis control/eradication programs and have been successfully used worldwide for decades. Strain 19 and RB51 are the approved B. abortus vaccines strains most commonly used to protect cattle against infection and abortion. However, due to some drawbacks shown by these vaccines much effort has been undertaken for the development of new vaccines, safer and more effective, that could also be used in other susceptible species of animals. In this paper, we present a review of the main aspects of the vaccines that have been used in the brucellosis control over the years and the current research advances in the development of new B. abortus vaccines.
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