When the tap runs dry: the physiological effects of acute experimental dehydration in Peromyscus eremicus.
When the tap runs dry: the physiological effects of acute experimental dehydration in Peromyscus eremicus.
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DOI：
10.1242/jeb.246386
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发表时间：
2023-12-01
影响因子：
2.8
通讯作者：
Macmanes, Matthew D.
中科院分区：
文献类型：
--
作者：
Blumstein, Danielle M.;Macmanes, Matthew D.
沙漠生物进化出了适应极端干旱环境的生理、生化和基因机制。研究适应沙漠的物种提供了一个独特的机会，以调查生物在地球上一些最恶劣的栖息地中所采用的生存策略。在沙漠环境中面临的两个主要挑战是保持水平衡和温度调节。我们收集了数据，在模拟沙漠环境和一个圈养的仙人掌小鼠（Peromyscus eremicus）的殖民地，并使用基于实验室的实验与真实的时间生理测量，能量消耗，水分流失率和呼吸交换率，表征缺水的反应。在实验的第一个24小时后，与有水的小鼠相比，没有水的小鼠的能量消耗显著降低，从而减少了水分流失。此外，我们观察到显著的质量损失，这可能是由于脱水相关的厌食症，通过减少废物和溶质负荷以及允许水从肾脏和胃肠道重吸收来限制液体损失的反应。最后，我们观察到体温与性别相关，与水合男性相比，没有水的男性保持体温，而没有水的女性体温下降，这表明女性的日常代谢抑制。 仙人掌小鼠表现出脱水厌食症，这是一种适应性反应，旨在通过减少废物和溶质负荷来限制体液流失，使它们能够在沙漠栖息地生存。
Desert organisms have evolved physiological, biochemical and genomic mechanisms to survive the extreme aridity of desert environments. Studying desert-adapted species provides a unique opportunity to investigate the survival strategies employed by organisms in some of the harshest habitats on Earth. Two of the primary challenges faced in desert environments are maintaining water balance and thermoregulation. We collected data in a simulated desert environment and a captive colony of cactus mice (Peromyscus eremicus) and used lab-based experiments with real time physiological measurements; energy expenditure, water loss rate and respiratory exchange rate, to characterize the response to water deprivation. Mice without access to water had significantly lower energy expenditures and in turn, reduced water loss compared to mice with access to water after the first 24 h of the experiment. Additionally, we observed significant mass loss that is probably due to dehydration-associated anorexia a response to limit fluid loss by reducing waste and the solute load as well as allowing water reabsorption from the kidneys and gastrointestinal tract. Finally, we observed body temperature correlated with sex, with males without access to water maintaining body temperature when compared with hydrated males, whereas body temperature decreased for females without access to water, suggesting daily metabolic depression in females. Cactus mice exhibit dehydration anorexia, which is an adaptive response aimed at limiting fluid loss by reducing waste and solute load, enabling them to survive in desert habitats.
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DOI：
10.1073/pnas.1613625114
发表时间：
2017-02-28
影响因子：
11.1
作者：
Albright, Thomas P.;Mutiibwa, Denis;Wolf, Blair O.
通讯作者：
Wolf, Blair O.
DOI：
10.1037/h0026772
发表时间：
1969-01-01
期刊：
JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY
影响因子：
--
作者：
FITZSIMO.JT;LEMAGNEN, J
通讯作者：
LEMAGNEN, J
影响因子：
2.6
作者：
Flores-Manzanero, Alejandro;Luna-Barcenas, Madisson A.;Vazquez-Dominguez, Ella
通讯作者：
Vazquez-Dominguez, Ella
影响因子：
3.5
作者：
Calisi, Rebecca M.;Austin, Suzanne H.;MacManes, Matthew D.
通讯作者：
MacManes, Matthew D.
影响因子：
3.7
作者：
Coppernoll-Houston, Dana;Potter, Christopher
通讯作者：
Potter, Christopher