Do executive function deficits predict later substance use disorders among adolescents and young adults?
Do executive function deficits predict later substance use disorders among adolescents and young adults?
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DOI：
10.1016/j.jaac.2010.11.010
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发表时间：
2011-02
影响因子：
13.3
通讯作者：
Biederman J
中科院分区：
文献类型：
--
作者：
Wilens TE;Martelon M;Fried R;Petty C;Bateman C;Biederman J
There is increasing interest regarding the risk and overlap of executive function deficits (EFDs) in stable cigarette smoking and substance use disorders (SUD). Therefore, we examined whether earlier EFD was a risk factor for subsequent cigarette smoking and SUD and further explored the relationship between EFD and SUD. We assessed 435 subjects at the five-year follow-up (232 cases of ADHD; mean age ± SD: 15.4 ± 3.43 and 203 controls: 16.3 ± 3.42 years) and again four to five years later as part of a prospective family study of ADHD youth. Individuals were assessed by structured psychiatric interview for psychopathology and SUD. EFD was categorically defined in an individual that had at least 2 out of 6 abnormal neuropsychological tests of executive functioning. At the final follow-up period, ADHD was found to be a significant predictor of stable cigarette smoking (p<0.01) and SUD into late adolescence and young adult years (p<0.01). However, EFDs were not associated with an increase in subsequent substance use outcomes. New onset stable cigarette smoking, but not SUD, was associated with subsequent EFD (p<0.01). Our results do not support the hypothesis that EFDs predicts later stable cigarette smoking or SUD in children with ADHD growing up. However, stable cigarette smoking is associated with subsequent EFD.
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影响因子：
--
作者：
Gale, Catharine R.;Deary, Ian J.;Batty, David
通讯作者：
Batty, David
DOI：
10.1089/cap.2005.15.742
发表时间：
2005-10-01
影响因子：
1.9
作者：
Gignac, M;Wilens, TE;Swezey, A
通讯作者：
Swezey, A
影响因子：
2.4
作者：
Cherbuin, Nicolas;Reglade-Meslin, Chantal;Anstey, Kaarin J.
通讯作者：
Anstey, Kaarin J.
影响因子：
6.9
作者：
Biederman, J;Monuteaux, MC;Faraone, SV
通讯作者：
Faraone, SV
影响因子：
4.1
作者：
Indlekofer, F.;Piechatzek, M.;Schuetz, C. G.
通讯作者：
Schuetz, C. G.