Of LAP, CUPS, and DRibbles - Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation.
Of LAP, CUPS, and DRibbles - Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation.
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DOI：
10.3389/fimmu.2015.00200
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发表时间：
2015
影响因子：
7.3
通讯作者：
Münz C
中科院分区：
文献类型：
--
作者：
Münz C
Macroautophagy delivers cytoplasmic constituents for lysosomal degradation. Because MHC class II molecules are loaded with lysosomal products for CD4+ T-cell stimulation, macroautophagy supports intracellular antigen processing onto MHC class II molecules. The molecular machinery of macroautophagy, however, does not only support this autophagic antigen processing, but seems to also modify extracellular antigen uptake for MHC class II presentation, antigen exocytosis, and packaging for improved cross-presentation onto MHC class I molecules. The different membrane trafficking pathways with LC3-associated phagocytosis, compartment for unconventional protein secretion, and DRibbles as well as the role that autophagic proteins play in them will be discussed in this review.
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DOI：
10.1083/jcb.201106098
发表时间：
2011-12-12
期刊：
The Journal of cell biology
影响因子：
--
作者：
Bruns C;McCaffery JM;Curwin AJ;Duran JM;Malhotra V
通讯作者：
Malhotra V
影响因子：
11.1
作者：
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通讯作者：
Munz, Christian
DOI：
10.4049/jimmunol.1302835
发表时间：
2014-02-15
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Ma J;Becker C;Reyes C;Underhill DM
通讯作者：
Underhill DM
影响因子：
29.7
作者：
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影响因子：
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通讯作者：
Sanjuan MA