Neurocognition as a predictor of response to evidence-based psychosocial interventions in schizophrenia: what is the state of the evidence?
Neurocognition as a predictor of response to evidence-based psychosocial interventions in schizophrenia: what is the state of the evidence?
复制标题
DOI：
10.1016/j.cpr.2011.02.008
复制
发表时间：
2011-06
影响因子：
12.8
通讯作者：
Kurtz, Matthew M.
中科院分区：
文献类型：
--
作者：
Kurtz, Matthew M.
功能状态受损是精神分裂症的一个标志，与神经认知方面的缺陷有关（例如，注意力、记忆力和解决问题的能力）。越来越多的循证行为干预措施已被开发出来，以解决功能状态的损害，但这些干预措施和神经认知障碍之间的关系还没有得到很好的理解。我们进行了一个综合性的，批判性的文献综述的研究表现的神经认知测试作为一个预测反应的循证行为治疗精神分裂症。行为治疗是根据患者结局研究小组（PORT）对实践和新兴领域的建议选择的。PsychINFO和MEDLINE/PUBMED数据库的综合检索确定了20项相关研究。结果显示：（1）在研究开始时测量的注意力和记忆力最常与社会技能培训计划的进展的近端测量相关，（2）神经认知功能的复合测量，以及注意力，记忆力和解决问题的能力，与工作治疗和支持就业计划的进展相关，以及心理社会康复的全面综合计划，而（3）神经认知测试的基线损害并未显示限制认知行为疗法的治疗研究的进展。这些研究结果的临床实践和未来的研究进行了讨论。
Impairment in functional status is a hallmark of schizophrenia that has been linked to deficits in aspects of neurocognition (e.g., attention, memory, and problem-solving). A growing number of evidence-based behavioral interventions have been developed to address impairment in functional status, yet the relationships between these interventions and neurocognitive impairment are not well-understood. We conducted a synthetic, critical literature review of studies of performance on neurocognitive tests as a predictor of response to evidence-based behavioral treatment in schizophrenia. Behavioral treatments were selected based on the Patient Outcomes Research Team (PORT) recommendations for practice and areas of emerging interest. Comprehensive searches of PsychINFO and MEDLINE/PUBMED databases identified 20 relevant studies. Results revealed that: (1) attention and memory measured at study entry were most frequently linked to proximal measures of progress in social skill training programs, (2) composite measures of neurocognitive function, as well attention, memory and problem-solving, were linked to progress in work therapy and supported employment programs, and comprehensive, integrated programs of psychosocial rehabilitation, while (3) baseline impairment on neurocogntive tests was not shown to limit progress in treatment studies of cognitive-behavioral therapy. The relevance of these findings for clinical practice and future research is discussed.
登录
查看更多内容
DOI：
10.1097/00004583-200011000-00015
发表时间：
2000-11-01
影响因子：
13.3
作者：
Hans, SL;Auerbach, JG;Marcus, J
通讯作者：
Marcus, J
影响因子：
6.6
作者：
Green, MF;Kern, RS;Mintz, J
通讯作者：
Mintz, J
影响因子：
3.3
作者：
Leclerc, C;Lesage, AD;Cyr, M
通讯作者：
Cyr, M
影响因子：
6.6
作者：
Bell, MD;Bryson, G
通讯作者：
Bryson, G
影响因子：
11.3
作者：
KERN, RS;GREEN, MF;SATZ, P
通讯作者：
SATZ, P