Social behaviours by Bacillus subtilis: quorum sensing, kin discrimination and beyond.
Social behaviours by Bacillus subtilis: quorum sensing, kin discrimination and beyond.
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DOI:
10.1111/mmi.14127
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发表时间:
2018-12
影响因子:
3.6
通讯作者:
Stanley-Wall NR
中科院分区:
文献类型:
--
作者:
Kalamara M;Spacapan M;Mandic-Mulec I;Stanley-Wall NR
Here, we review the multiple mechanisms that the Gram‐positive bacterium Bacillus subtilis uses to allow it to communicate between cells and establish community structures. The modes of action that are used are highly varied and include routes that sense pheromone levels during quorum sensing and control gene regulation, the intimate coupling of cells via nanotubes to share cytoplasmic contents, and long‐range electrical signalling to couple metabolic processes both within and between biofilms. We explore the ability of B. subtilis to detect ‘kin’ (and ‘cheater cells’) by looking at the mechanisms used to potentially ensure beneficial sharing (or limit exploitation) of extracellular ‘public goods’. Finally, reflecting on the array of methods that a single bacterium has at its disposal to ensure maximal benefit for its progeny, we highlight that a large future challenge will be integrating how these systems interact in mixed‐species communities.
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