The oral microbiota: living with a permanent guest.

The oral microbiota: living with a permanent guest.
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DOI:
10.1089/dna.2009.0874
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发表时间:
2009-08
影响因子:
3.1
通讯作者:
Yilmaz O
Yilmaz O
中科院分区:
生物学4区
文献类型:
--
作者:
Avila M;Ojcius DM;Yilmaz O

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健康人的口腔含有数百种不同的细菌、病毒和真菌。其中许多可以结合形成生物膜,这些生物膜对机械压力或抗生素治疗具有抵抗力。大多数也是共生物种,但它们可以在对环境变化或口腔中其他触发因素的反应中致病,包括个人卫生质量。口腔微生物组的复杂性正在通过新开发的元基因组学工具来表征。口腔微生物群对健康和疾病的贡献正吸引着越来越多的细胞生物学家、微生物学家和免疫学家的兴趣。
The oral cavity of healthy individuals contains hundreds of different bacterial, viral, and fungal species. Many of these can associate to form biofilms, which are resistant to mechanical stress or antibiotic treatment. Most are also commensal species, but they can become pathogenic in responses to changes in the environment or other triggers in the oral cavity, including the quality of an individual’s personal hygiene. The complexity of the oral microbiome is being characterized through the newly developed tools of metagenomics. How the microbiome of the oral cavity contributes to health and disease is attracting the interest of a growing number of cell biologists, microbiologists, and immunologists.
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