24-h Nitrogen dioxide concentration is associated with cooking behaviors and an increase in rescue medication use in children with asthma.
24-h Nitrogen dioxide concentration is associated with cooking behaviors and an increase in rescue medication use in children with asthma.
复制标题
DOI：
10.1016/j.envres.2017.07.052
复制
发表时间：
2017-11
影响因子：
8.3
通讯作者：
Hansel NN
中科院分区：
文献类型：
--
作者：
Paulin LM;Williams D'L;Peng R;Diette GB;McCormack MC;Breysse P;Hansel NN
暴露于二氧化氮（NO2），燃烧的副产品，与儿童哮喘控制不良有关。我们试图确定使用燃气厨房用具是否与24小时室内NO2浓度相关，以及这些浓度是否与儿童哮喘发病率相关。5 - 12岁哮喘儿童符合条件。平均24小时NO2浓度在厨房里测量了四天的采样期和燃气灶的使用被捕获的时间活动日记。分析了炉灶、烤箱使用与NO2日浓度的关系。纵向分析评估了每日NO2暴露对症状、吸入器使用和肺功能的影响。多变量模型进行了调整，年龄，性别，季节和母亲的教育。30名儿童提供了126个参与日的采样。平均室内24小时NO2浓度为58（48）ppb，中位数（范围）为45（12 - 276）ppb。所有家庭都有煤气炉和火炉。使用厨房用具每小时与24小时NO2浓度增加18ppb相关。在纵向多变量分析中，前一天NO2每增加10倍与夜间吸入器使用增加相关（OR = 4.9，p = 0.04）。NO2与肺功能或哮喘症状之间无相关性。前一天24小时NO2浓度较高与哮喘儿童夜间吸入器使用增加相关。
Exposure to nitrogen dioxide (NO2), a by product of combustion, is associated with poor asthma control in children. We sought to determine whether gas-fueled kitchen appliance use is associated with 24-hour indoor NO2 concentrations and whether these concentrations are associated with asthma morbidity in children. Children aged 5–12 years old with asthma were eligible. Mean 24-hour NO2 concentration was measured in the kitchen over a four-day sampling period and gas stove use was captured in time activity diaries. The relationship between stove and oven use and daily NO2 concentration was analyzed. Longitudinal analysis assessed the effect of daily NO2 exposure on symptoms, inhaler use, and lung function. Multivariate models were adjusted for age, sex, season, and maternal education. Thirty children contributed 126 participant days of sampling. Mean indoor 24-hour NO2 concentration was 58(48) ppb with a median (range) of 45(12-276) ppb. All homes had gas stoves and furnaces. Each hour of kitchen appliance use was associated with an 18ppb increase in 24-hour NO2 concentration. In longitudinal multivariate analysis, each ten-fold increase in previous-day NO2 was associated with increased night time inhaler use (OR=4.9, p=0.04). There were no associations between NO2 and lung function or asthma symptoms. Higher previous-day 24-hour concentration of NO2 is associated with increased night time inhaler use in children with asthma.
登录
查看更多内容
DOI：
10.1097/01.jom.0000215802.43229.62
发表时间：
2006-05-01
影响因子：
3.2
作者：
Nitschke, Monika;Pilotto, Louis S.;Hiller, Janet E.
通讯作者：
Hiller, Janet E.
影响因子：
5
作者：
Dimitroulopoulou, C;Ashmore, MR;Kinnersley, RP
通讯作者：
Kinnersley, RP
影响因子：
5
作者：
Franklin, Peter;Runnion, Tina;Dingle, Peter
通讯作者：
Dingle, Peter
影响因子：
5
作者：
NEAS, LM;DOCKERY, DW;FERRIS, BG
通讯作者：
FERRIS, BG
影响因子：
8.3
作者：
Breysse, PN;Buckley, TJ;Eggleston, PA
通讯作者：
Eggleston, PA