Malaria incidence in Limpopo Province, South Africa, 1998-2007.
Malaria incidence in Limpopo Province, South Africa, 1998-2007.
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DOI：
10.1186/1475-2875-7-162
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发表时间：
2008-08-25
期刊：
影响因子：
3
通讯作者：
Grobusch MP
中科院分区：
文献类型：
--
作者：
Gerritsen AA;Kruger P;van der Loeff MF;Grobusch MP
疟疾在南非北部和东部的低海拔地区流行，具有季节性传播。这项描述性研究的目的是概述1998-1999年至2006-2007年四个季节林波波省的疟疾发病率和死亡率，并查明随时间和地点的趋势。通过省疟疾信息系统可获得常规收集的确诊疟疾病例和死亡数据。为了计算发病率，从南非统计局获得了人口估计数(按性别、年龄和地区)。趋势的卡方检验被用来检测疟疾发病率在不同季节的时间趋势，以及按年龄组的病例死亡率(CFR)的趋势。用卡方检验计算男女发病率和CFR的差异以及不同年龄组发病率的差异。总共报告了58768例疟疾病例，包括628例死亡。平均发病率为124.5/10万人年，平均病死率为1.1%/季。随着时间的推移，发病率有下降的趋势(p<；0.001)，从1998年至1999年的173.0下降到2006年至2007年的50.9%。在整个期间，CFR相当稳定。男性的平均发病率高于女性(145.8比105.6；P<；0.001)；男女的CFR(1.1%)相似。发病率以172.8~4岁最低(78.30%)，35~39岁最高(79.7%)，40岁以后逐渐下降(60岁≥为84.4%)。CFR值随年龄增长而增加(≥60岁时为3.8%)。不同地区的发病率差异很大；温贝的发病率最高(328.2)，塞胡库纳最低(5.5%)。这项研究提供的信息可作为基线数据，以确定一段时间内林波波省疟疾的进程和分布情况。在研究期间，发病率有下降的趋势。此外，这项研究解决了在一系列疫情易发环境中需要更好的数据的问题。
Malaria is endemic in the low-altitude areas of the northern and eastern parts of South Africa with seasonal transmission. The aim of this descriptive study is to give an overview of the malaria incidence and mortality in Limpopo Province for the seasons 1998–1999 to 2006–2007 and to detect trends over time and place. Routinely collected data on diagnosed malaria cases and deaths were available through the provincial malaria information system. In order to calculate incidence rates, population estimates (by sex, age and district) were obtained from Statistics South Africa. The Chi squared test for trend was used to detect temporal trends in malaria incidence over the seasons, and a trend in case fatality rate (CFR) by age group. The Chi squared test was used to calculate differences in incidence rate and CFR between both sexes and in incidence by age group. In total, 58,768 cases of malaria were reported, including 628 deaths. The mean incidence rate was 124.5 per 100,000 person-years and the mean CFR 1.1% per season. There was a decreasing trend in the incidence rate over time (p < 0.001), from 173.0 in 1998–1999 to 50.9 in 2006–2007. The CFR was fairly stable over the whole period. The mean incidence rate in males was higher than in females (145.8 versus 105.6; p < 0.001); the CFR (1.1%) was similar for both sexes. The incidence rate was lowest in 0–4 year olds (78.3), it peaked at the ages of 35–39 years (172.8), and decreased with age from 40 years (to 84.4 for those ≥ 60 years). The CFR increased with increasing age (to 3.8% for those ≥ 60 years). The incidence rate varied widely between districts; it was highest in Vhembe (328.2) and lowest in Sekhukhune (5.5). Information from this study may serve as baseline data to determine the course and distribution of malaria in Limpopo province over time. In the study period there was a decreasing trend in the incidence rate. Furthermore, the study addresses the need for better data over a range of epidemic-prone settings.
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影响因子：
168.9
作者：
Price, RN;Nosten, F;White, NJ
通讯作者：
White, NJ
DOI：
10.4269/ajtmh.2004.71.136
发表时间：
2004-08-01
影响因子：
3.3
作者：
Worrall, E;Rietveld, A;Delacollette, C
通讯作者：
Delacollette, C
影响因子：
11.8
作者：
M端hlberger, N;Jelinek, T;Myrvang, B
通讯作者：
Myrvang, B
DOI：
10.1016/s0169-4758(98)01296-4
发表时间：
1998-09-01
期刊：
PARASITOLOGY TODAY
影响因子：
--
作者：
Alles, HK;Mendis, KN;Carter, R
通讯作者：
Carter, R
影响因子：
3.3
作者：
Craig, MH;Kleinschmidt, I;Sharp, BL
通讯作者：
Sharp, BL