Spatial neglect treatment: The brain's spatial-motor Aiming systems.
Spatial neglect treatment: The brain's spatial-motor Aiming systems.
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DOI：
10.1080/09602011.2020.1862678
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发表时间：
2022-06
影响因子：
2.7
通讯作者：
中科院分区：
文献类型：
--
作者：
Animal and human literature supports spatial-motor “Aiming” bias, a frontal-subcortical syndrome, as a core deficit in spatial neglect. However, spatial neglect treatment studies rarely assess Aiming errors. Two knowledge gaps result: spatial neglect rehabilitation studies fail to capture the impact on motor-exploratory aspects of functional disability. Also, across spatial neglect treatment studies, discrepant treatment effects may also result from sampling different proportions of patients with Aiming bias. We review behavioral evidence for Aiming spatial neglect, and demonstrate the importance of measuring and targeting Aiming bias for treatment, by reviewing literature on Aiming spatial neglect and prism adaptation treatment, and presenting new preliminary data on bromocriptine treatment. Finally, we review neuroanatomical and network disruption that may give rise to Aiming spatial neglect. Because Aiming spatial neglect predicts prism adaptation treatment response, assessment may broaden the ability of rehabilitation research to capture functionally-relevant disability. Frontal brain lesions predict both the presence of Aiming spatial neglect, and a robust response to some spatial neglect interventions. Research is needed that co-stratifies spatial neglect patients by lesion location and Aiming spatial neglect, to personalize spatial neglect rehabilitation and perhaps even open a path to spatial retraining as a means of promoting better mobility after stroke.
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影响因子：
4.3
作者：
Chen P;Chen CC;Hreha K;Goedert KM;Barrett AM
通讯作者：
Barrett AM
影响因子：
1.8
作者：
Archambault, P. S.;Ferrari-Toniolo, S.;Battaglia-Mayer, A.
通讯作者：
Battaglia-Mayer, A.
DOI：
10.1016/j.rehab.2015.12.005
发表时间：
2017-06-01
影响因子：
4.6
作者：
Azouvi, Philippe
通讯作者：
Azouvi, Philippe
影响因子：
64.8
作者：
CARLI, M;EVENDEN, JL;ROBBINS, TW
通讯作者：
ROBBINS, TW
DOI：
10.1016/s0003-9993(99)90205-8
发表时间：
1999-05-01
影响因子：
4.3
作者：
Barrett, AM;Crucian, GP;Heilman, KM
通讯作者：
Heilman, KM