Parallel and serial processing in dual-tasking differentially involves mechanisms in the striatum and the lateral prefrontal cortex

Parallel and serial processing in dual-tasking differentially involves mechanisms in the striatum and the lateral prefrontal cortex
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双任务中的并行和串行处理不同地涉及纹状体和外侧前额皮质的机制

DOI:
10.1007/s00429-014-0847-0
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发表时间:
2015
影响因子:
3.1
通讯作者:
Yildiz
Yildiz
中科院分区:
医学3区
文献类型:
--
作者:
Yildiz

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众所周知,外侧前额叶皮层和基底神经节对于反应选择过程非常重要,在双任务情况下也是如此。然而,双任务情况下的响应选择可以使用不同的模式来实现,从并行选择到更串行的响应选择。目前尚不清楚双任务期间这些处理模式的差异是否具有不同的功能神经解剖学相关性。在这项功能磁共振成像研究中,我们分析了心理不应期范式中的表现。在这个范例中,我们设计了一个 PRP 任务,其中我们改变两个任务之间短刺激和长刺激开始异步的频率。使用数学约束,我们解释了这种操作对于处理模式(从更串行到更并行的响应选择)的影响。相比之下,这些模块表明,在更多并行处理的约束下,双任务中的响应选择是由在纹状体水平上运行的机制介导的,而在更多串行处理约束下的响应选择是通过在外侧前额叶皮层中运行的机制介导的。结果表明,外侧前额叶和纹状体区域针对双重任务中的某些处理模式进行了“优化”。
The lateral prefrontal cortex and the basal ganglia are known to be important for response selection processes, also in dual-task situations. However, response selection in dual-task situations can be achieved using different modes ranging from a parallel selection to a more serial selection of responses. Nothing is known whether differences in these processing modes during dual-tasking have distinct functional neuroanatomical correlates. In this fMRI study we analyzed performance in a psychological refractory period paradigm. In this paradigm we design a PRP task where we vary the frequency of short and long stimulus onset asynchronies between the two tasks. Using mathematical constraints we interpret the effects of this manipulation with respect to processing modes ranging from more serial to more parallel response selection. Contrastingly these blocks showed that response selection in dual-tasking under the constraint of more parallel processing is mediated by mechanisms operating at the striatal level, while response selection under the constraint of more serial processing is mediated via mechanisms operating in the lateral prefrontal cortex. The results suggest that lateral prefrontal and striatal regions are ‘optimized’ for a certain processing modes in dual tasking.
DOI: 10.1093/cercor/bht066
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影响因子: 3.7
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影响因子: 2.7
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