The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data.

The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data.
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1990 - 2014年中国登革热的流行病学变化:对全国25年的监视数据的描述性分析。

DOI:
10.1186/s12916-015-0336-1
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发表时间:
2015-04-28
期刊:
影响因子:
9.3
通讯作者:
Yu H
Yu H
中科院分区:
医学1区
文献类型:
--
作者:
Lai S;Huang Z;Zhou H;Anders KL;Perkins TA;Yin W;Li Y;Mu D;Chen Q;Zhang Z;Qiu Y;Wang L;Zhang H;Zeng L;Ren X;Geng M;Li Z;Tatem AJ;Hay SI;Yu H

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自1989年9月1日起,登革热在中国成为一种必须报告的疾病。在过去25年中国社会经济发生巨大变化的过程中,每年都有病例报告,并在2014年达到历史最高水平。本研究描述了这一时期中国登革热流行病学的变化,以确定高风险地区和季节,并为登革热预防和控制活动提供信息。我们使用1990-2014年的应通报监测数据描述了中国大陆登革热的发病率和分布,其中包括2005-2014年的输入性和本土病例分类。从1990年到2014年,中国大陆报告了69,321例登革热病例,其中包括11例死亡,相当于每百万居民中有2.2例病例。2014年记录的最高数字(47,056例)。受影响的省份数量有所增加,从1990-2000年期间每年3个省的中位数(范围:1至5个省)增加到2001-2014年期间每年14.5个省的中位数(范围:5至26个省)。在2005-2014年期间,几乎每个月都有输入性病例报告,28个省(90.3%)受到影响。然而,99.8%的土著病例发生在7月至11月之间。报告本土病例的地区已从中国南方沿海省份和邻近东南亚的省份扩大到中国中部。登革热病毒血清型1、2、3和4均在2009-2014年期间被检测到。在中国,自2000年以来,登革热影响的地区有所扩大,自2012年以来,输入性和本土性登革热的发病率稳步上升。应调整监测和控制策略,以应对这些变化,进一步的研究应探索这些趋势的驱动因素。请参阅相关文章:http://dx.doi.org/10.1186/s12916-015-0345-0本文的在线版本(doi:10.1186/s12916-015-0336-1)包含补充材料,可供授权用户使用。
Dengue has been a notifiable disease in China since 1 September 1989. Cases have been reported each year during the past 25 years of dramatic socio-economic changes in China, and reached a historical high in 2014. This study describes the changing epidemiology of dengue in China during this period, to identify high-risk areas and seasons and to inform dengue prevention and control activities. We describe the incidence and distribution of dengue in mainland China using notifiable surveillance data from 1990-2014, which includes classification of imported and indigenous cases from 2005-2014. From 1990-2014, 69,321 cases of dengue including 11 deaths were reported in mainland China, equating to 2.2 cases per one million residents. The highest number was recorded in 2014 (47,056 cases). The number of provinces affected has increased, from a median of three provinces per year (range: 1 to 5 provinces) during 1990-2000 to a median of 14.5 provinces per year (range: 5 to 26 provinces) during 2001-2014. During 2005-2014, imported cases were reported almost every month and 28 provinces (90.3%) were affected. However, 99.8% of indigenous cases occurred between July and November. The regions reporting indigenous cases have expanded from the coastal provinces of southern China and provinces adjacent to Southeast Asia to the central part of China. Dengue virus serotypes 1, 2, 3, and 4 were all detected from 2009-2014. In China, the area affected by dengue has expanded since 2000 and the incidence has increased steadily since 2012, for both imported and indigenous dengue. Surveillance and control strategies should be adjusted to account for these changes, and further research should explore the drivers of these trends. Please see related article: http://dx.doi.org/10.1186/s12916-015-0345-0 The online version of this article (doi:10.1186/s12916-015-0336-1) contains supplementary material, which is available to authorized users.
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