Hearing and orally mimicking different acoustic-semantic categories of natural sound engage distinct left hemisphere cortical regions.
Hearing and orally mimicking different acoustic-semantic categories of natural sound engage distinct left hemisphere cortical regions.
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DOI：
10.1016/j.bandl.2018.05.002
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发表时间：
2018-08
影响因子：
2.5
通讯作者：
Brefczynski-Lewis JA
中科院分区：
文献类型：
--
作者：
Lewis JW;Silberman MJ;Donai JJ;Frum CA;Brefczynski-Lewis JA
口腔模仿被认为是婴儿口语系统神经发育、古人类语言进化的一个重要过程，也是一个可能有助于中风患者康复的过程。使用功能磁共振成像（fMRI），我们之前报道了介导特定类别自然声音感知的听觉皮层通路的分歧。然而，目前尚不清楚大脑的这种基本感觉组织是否或如何与运动输出（例如声音模仿）相关。在这里，我们使用功能磁共振成像，揭示了优先于听觉的激活大脑区域的分离，以及模仿动物动作声音与动物发声的口头模仿作为不同的声学语义类别。这种功能分离可能反映了基本皮质结构的组成部分，该结构将处理自然声音的声学语义普遍性的系统与在类别级别上介导口腔模仿的运动相关系统联系起来。对涉及口腔模仿不同方面的不同大脑区域的观察可能为中风后功能能力康复的靶向治疗提供信息。
Oral mimicry is thought to represent an essential process for the neurodevelopment of spoken language systems in infants, the evolution of language in hominins, and a process that could possibly aid recovery in stroke patients. Using functional magnetic resonance imaging (fMRI), we previously reported a divergence of auditory cortical pathways mediating perception of specific categories of natural sounds. However, it remained unclear if or how this fundamental sensory organization by the brain might relate to motor output, such as sound mimicry. Here, using fMRI, we revealed a dissociation of activated brain regions preferential for hearing with the intent to imitate and the oral mimicry of animal action sounds versus animal vocalizations as distinct acoustic-semantic categories. This functional dissociation may reflect components of a rudimentary cortical architecture that links systems for processing acoustic-semantic universals of natural sound with motor-related systems mediating oral mimicry at a category level. The observation of different brain regions involved in different aspects of oral mimicry may inform targeted therapies for rehabilitation of functional abilities after stroke.
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影响因子：
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作者：
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