Patterns of methamphetamine use during pregnancy: results from the Infant Development, Environment, and Lifestyle (IDEAL) Study.
Patterns of methamphetamine use during pregnancy: results from the Infant Development, Environment, and Lifestyle (IDEAL) Study.
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DOI：
10.1007/s10995-009-0491-0
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发表时间：
2010-07
影响因子：
2.3
通讯作者：
Lester BM
中科院分区：
文献类型：
--
作者：
Della Grotta S;LaGasse LL;Arria AM;Derauf C;Grant P;Smith LM;Shah R;Huestis M;Liu J;Lester BM
本研究的目的是描述妊娠期间甲基苯丙胺 (MA) 使用模式的特征，检查 MA 使用模式是否与社会人口特征和产前护理相关，并检验妊娠期间持续或增加 MA 使用与更多使用其他非法药物相关的假设。该样本由 191 名使用 MA 的母亲组成，她们参加了一项关于产前 MA 暴露的大规模多中心研究。物质使用模式通过母亲自我报告通过物质使用清单 (SUI) 进行评估，其中包括有关 MA 使用的详细信息，包括怀孕每个三个月期间的频率、数量和最大使用量。该研究表明，平均而言，MA 的使用率在怀孕的三个三个月期间有所下降（84.3% vs. 56.0% vs. 42.4%），并且从妊娠早期到第三个月，MA 的使用频率有所下降（每周 3.1 天 vs. 2.4 天/周）。对个体模式的仔细检查显示，29.3% 的女性在怀孕期间保持持续的高频率，9.4% 的频率增加，25.7% 的女性具有稳定的低/中等模式，35.6% 的女性在怀孕过程中降低了 MA 频率。这四个群体的社会人口特征没有差异；与一贯高使用量组相比，减少使用 MA 的女性的产前检查次数明显增多，但她们在怀孕期间最有可能使用酒精。总之，本文阐明了该社区样本中 MA 使用的不同模式。大约有三分之一使用 MA 的母亲可被归类为持续高使用率，其使用情况对其自身及其婴儿造成最大风险，包括在整个怀孕期间高水平使用 MA 和较少的产前护理就诊。总体而言，我们发现怀孕期间 MA 的使用量有所下降；然而，相当一部分使用者的 MA 使用率持续较高或不断增加，而那些降低 MA 频率的使用者则有较高的多种药物使用率。未来的研究将调查这些模式与新生儿结局的关联。
The objectives of this study are to characterize methamphetamine (MA) usage patterns during pregnancy, examine whether patterns of MA use are associated with sociodemographic characteristics and prenatal care, and test the hypothesis that persistent or increasing MA use during pregnancy is associated with greater use of other illicit drugs. The sample consisted of 191 MA-using mothers who participated in a large-scale multi-site study of prenatal MA exposure. Patterns of substance use were assessed by maternal self-report via the Substance Use Inventory (SUI), which included detailed information about MA use, including frequency, quantity, and maximum use during each trimester of pregnancy. The study demostrated that on average, the prevalence of MA use decreased over the three trimesters of pregnancy (84.3% vs. 56.0% vs. 42.4%), and decreased frequency was observed among users from the first trimester to the third (3.1 vs. 2.4 vs. 1.5 days/week). Closer examination of the individual patterns revealed that 29.3% of women maintained consistently high frequency, 9.4% increased frequency, 25.7% had a stable low/moderate pattern, and 35.6% decreased their frequency of MA over the course of pregnancy. These four groups did not differ in sociodemographic characteristics; women who decreased their use of MA had significantly more prenatal visits compared to the consistently high-use group, but were the most likely to use alcohol during their pregnancy. In conclusion, this article elucidated the different patterns of MA use in this community sample. Approximately, one third of MA-using mothers could be classified as consistently high users with a profile of use with the greatest risk to themselves and potentially to their infants including high levels of MA use throughout pregnancy and fewer prenatal care visits. Overall, we found that MA use declined across pregnancy; however, a substantial proportion of users had consistently high or increasing MA use, while those who decreased their MA frequency had a higher prevalence of polydrug use. Future research will investigate the association of these patterns with neonatal outcomes.
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影响因子：
8
作者：
Smith, Lynne M.;LaGasse, Linda L.;Lester, Barry M.
通讯作者：
Lester, Barry M.
影响因子：
2.9
作者：
Smith, Lynne M.;LaGasse, Linda L.;Lester, Barry M.
通讯作者：
Lester, Barry M.
影响因子：
2.3
作者：
Arria, Amelia M.;Derauf, Chris;Lester, Barry
通讯作者：
Lester, Barry
影响因子：
1.7
作者：
Derauf, C;Katz, AR;Easa, D
通讯作者：
Easa, D
影响因子：
5.1
作者：
JACOBSON, JL;JACOBSON, SW;SHANKARAN, S
通讯作者：
SHANKARAN, S