Quality Control and Reproducibility in M-Mode, Two-Dimensional, and Speckle Tracking Echocardiography Acquisition and Analysis: The CARDIA Study, Year 25 Examination Experience.
Quality Control and Reproducibility in M-Mode, Two-Dimensional, and Speckle Tracking Echocardiography Acquisition and Analysis: The CARDIA Study, Year 25 Examination Experience.
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DOI：
10.1111/echo.12832
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发表时间：
2015-08
期刊：
影响因子：
--
通讯作者：
Lima JA
中科院分区：
文献类型：
--
作者：
Armstrong AC;Ricketts EP;Cox C;Adler P;Arynchyn A;Liu K;Stengel E;Sidney S;Lewis CE;Schreiner PJ;Shikany JM;Keck K;Merlo J;Gidding SS;Lima JA
很少有大型研究描述心血管超声的质量控制程序和再现性结果，特别是在斑点跟踪（STE）等新技术中。我们在CARDIA研究Y25检查（2010-2011）中评价了超声心动图评估性能，并报告了质量控制和再现性项目的结果，该项目旨在评估场中心图像采集和阅读中心（RC）准确性。CARDIA Y25检查在4个美国现场中心进行了3，475次超声心动图检查，并在阅读中心进行了分析，评估了标准超声心动图（LA尺寸、主动脉根、LV质量、LV舒张末期容积[LVEDV]、射血分数[LVEF]）和STE（2腔和4腔纵向、周向和径向应变）。使用组内相关系数（ICC）、变异系数（CV）和Bland-Altman图评估生殖能力。对于标准超声心动图再现性，LV质量和LVEDV的CV始终高于10%，主动脉根部低于6%。在标准超声心动图中，超声医师内主动脉根部和LV质量的ICC值最可靠。STE中，短轴和四腔室的正确追踪节段数超过80%，而两腔室的正确追踪节段数为58%。纵向应变参数是最强大的和径向应变表现出最高的变化。将场中心与回波RC STE读数进行比较，平均差异范围为0.4%至4.1%，ICC范围为0.37至0.66，纵向应变结果稳健。CARDIA研究中的超声心动图图像采集和阅读过程具有高度可重复性，包括STE分析的稳健结果。在大型队列研究中，一致的质量控制可能会增加超声心动图测量的可靠性。
Few large studies describe quality control procedures and reproducibility findings in cardiovascular ultra-sound, particularly in novel techniques such as Speckle Tracking (STE). We evaluate the echocardiography assessment performance in the CARDIA study Y25 examination (2010-2011) and report findings from a quality control and reproducibility program conducted to assess Field Center image acquisition and Reading Center (RC) accuracy. The CARDIA Y25 examination had 3,475 echocardiograms performed in 4 US Field Centers and analyzed in a Reading Center, assessing standard echocardiography (LA dimension, aortic root, LV mass, LV end-diastolic volume [LVEDV], ejection fraction [LVEF]), and STE (2- and 4-chamber longitudinal, circumferential, and radial strains). Reproducibility was assessed using intra-class correlation coefficients (ICC), coefficients of variation (CV), and Bland-Altman plots. For standard echocardiography reproducibility, LV mass and LVEDV consistently had CV above 10% and aortic root below 6%. Intra-sonographer aortic root and LV mass had the most robust values of ICC in standard echocardiography. For STE, the number of properly tracking segments was above 80% in short-axis and 4-chamber and 58% in 2-chamber. Longitudinal strain parameters were the most robust and radial strain showed the highest variation. Comparing Field Centers with Echo RC STE readings, mean differences ranged from 0.4% to 4.1% and ICC from 0.37 to 0.66, with robust results for longitudinal strains. Echocardiography image acquisition and reading processes in the CARDIA study were highly reproducible, including robust results for STE analysis. Consistent quality control may increase the reliability of echocardiography measurements in large cohort studies.
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