Rapid detection of transition metals in welding fumes using paper-based analytical devices.

Rapid detection of transition metals in welding fumes using paper-based analytical devices.
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使用基于纸张的分析设备对焊接烟雾中过渡金属的快速检测。

DOI:
10.1093/annhyg/met078
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发表时间:
2014-05
期刊:
The Annals of occupational hygiene
影响因子:
--
通讯作者:
Volckens J
Volckens J
中科院分区:
其他
文献类型:
--
作者:
Cate DM;Nanthasurasak P;Riwkulkajorn P;L'Orange C;Henry CS;Volckens J

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颗粒物(PM)中的金属被认为是许多病理学的驱动因素。尽管与颗粒金属有关的危害,但由于与监测有关的成本和努力,很少评估高危工人的个人暴露。因此,只对一小部分受照射的劳动力进行常规照射评估。本研究的目的是评估一种相对较新的技术,微流体纸基分析装置(µ PAD),用于测量焊接烟雾中的金属含量。从三种常见的焊接技术(保护金属电弧焊,金属惰性气体,钨极惰性气体保护焊)的烟雾进行了采样,在两个焊接车间。使用电感耦合等离子体发射光谱法(ICP-OES)测量并独立验证酸浸提的Fe、Cu、Ni和Cr浓度。µPAD传感器的结果与ICP-OES分析一致;两种方法在>80%的分析样品中得到了统计学相似的结果。µPAD技术的分析成本比ICP-OES的市场价格成本低约50倍。此外,µPAD方法能够提供当天的结果(而ICP实验室分析需要数周)。这项工作的结果表明,µPAD传感器是一个可行的,但廉价的替代传统的分析方法,过渡金属焊接烟雾PM。这些传感器有可能在给定的资源成本下实现更高水平的危险监测,特别是在资源有限的环境中。
Metals in particulate matter (PM) are considered a driving factor for many pathologies. Despite the hazards associated with particulate metals, personal exposures for at-risk workers are rarely assessed due to the cost and effort associated with monitoring. As a result, routine exposure assessments are performed for only a small fraction of the exposed workforce. The objective of this research was to evaluate a relatively new technology, microfluidic paper-based analytical devices (µPADs), for measuring the metals content in welding fumes. Fumes from three common welding techniques (shielded metal arc, metal inert gas, and tungsten inert gas welding) were sampled in two welding shops. Concentrations of acid-extractable Fe, Cu, Ni, and Cr were measured and independently verified using inductively coupled plasma-optical emission spectroscopy (ICP-OES). Results from the µPAD sensors agreed well with ICP-OES analysis; the two methods gave statistically similar results in >80% of the samples analyzed. Analytical costs for the µPAD technique were ~50 times lower than market-rate costs with ICP-OES. Further, the µPAD method was capable of providing same-day results (as opposed several weeks for ICP laboratory analysis). Results of this work suggest that µPAD sensors are a viable, yet inexpensive alternative to traditional analytic methods for transition metals in welding fume PM. These sensors have potential to enable substantially higher levels of hazard surveillance for a given resource cost, especially in resource-limited environments.
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