Exploring the relationships between adolescent alcohol misuse and later life health outcomes.
Exploring the relationships between adolescent alcohol misuse and later life health outcomes.
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DOI：
10.1111/acer.14917
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发表时间：
2022-09
期刊：
影响因子：
--
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中科院分区：
文献类型：
--
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我们试图澄清青少年酒精滥用对成年人身体健康和主观幸福感的影响。为此，我们调查了青少年酒精滥用与中年早期身体健康和生活满意度之间的直接联系，以及随后的酒精问题对这些结果的间接影响。样本包括来自FinnTwin 16研究的2733对双胞胎（32%为单卵双胞胎; 52%为女性）。青少年酒精滥用是醉酒频率，酒精使用频率和16岁，17岁和18.5岁的酒精问题的复合物。中年早期的结果包括34岁时的躯体症状、自评健康和生活满意度。作为间接效应分析的一部分，研究的中介包括24岁和34岁时罗格斯酒精问题指数中的酒精问题。应用了系列中介和双胞胎比较模型，包括青春期和中年早期的协变量。青少年酒精滥用与中年早期的身体健康和生活满意度之间存在微弱的直接关联。然而，有更有力的证据表明间接影响，即年轻人和中年早期的酒精问题连续介导青少年酒精滥用和中年早期躯体症状之间的关系（β = 0.03，95%CI [0.03，0.04]）、自评健康（β = −0.02，95%CI [−0.03，−0.01]）和生活满意度（β = −0.03，CI [−0.04，−0.02]）。这些系列中介效应在双胞胎比较分析中是稳健的。这些结果提供的证据表明，酒精问题是青少年滥用酒精和整个生命周期健康状况不佳的主要驱动因素。在来自芬兰的2，733对双胞胎样本中，我们发现年轻人和中年早期酒精问题连续介导青少年酒精滥用与更高的躯体症状，更低的自我评价健康和更低的生活满意度之间的关系。在使用双胞胎比较设计严格控制潜在混杂遗传和环境因素后，这些效应是稳健的。这些发现表明，酒精问题是青少年滥用酒精和整个生命周期健康状况不佳的主要驱动因素。
We sought to clarify the impact of adolescent alcohol misuse on adult physical health and subjective well‐being. To do so, we investigated both the direct associations between adolescent alcohol misuse and early midlife physical health and life satisfaction and the indirect effects on these outcomes attributable to subsequent alcohol problems. The sample included 2733 twin pairs (32% monozygotic; 52% female) from the FinnTwin16 study. Adolescent alcohol misuse was a composite of frequency of drunkenness, frequency of alcohol use, and alcohol problems at ages 16, 17, and 18.5. The early midlife outcomes included somatic symptoms, self‐rated health, and life satisfaction at age 34. The mediators examined as part of the indirect effect analyses included alcohol problems from the Rutgers Alcohol Problem Index at ages 24 and 34. Serial mediation and co‐twin comparison models were applied and included covariates from adolescence and early midlife. There were weak direct associations between adolescent alcohol misuse and early midlife physical health and life satisfaction. However, there was stronger evidence for indirect effects, whereby young adult and early midlife alcohol problems serially mediated the relationship between adolescent alcohol misuse and early midlife somatic symptoms (β = 0.03, 95% CI [0.03, 0.04]), self‐rated health (β = −0.02, 95% CI [−0.03, −0.01]), and life satisfaction (β = −0.03, CI [−0.04, −0.02]). These serial mediation effects were robust in co‐twin comparison analyses. These results provide evidence that alcohol problems are a primary driver linking adolescent alcohol misuse and poor health outcomes across the lifespan. In a sample of 2,733 twin pairs from Finland, we found evidence that young adult and early midlife alcohol problems serially mediate the relationship between adolescent alcohol misuse and higher somatic symptoms, lower self‐rated health, and lower life satisfaction in early midlife. These effects were robust following rigorous control for potentially confounding genetic and environmental factors using a co‐twin comparison design. These findings indicate alcohol problems are a primary driver linking adolescent alcohol misuse and poor health outcomes across the lifespan.
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DOI：
10.1080/10705519909540118
发表时间：
1999-01-01
影响因子：
6
作者：
Hu, Li-tze;Bentler, Peter M.
通讯作者：
Bentler, Peter M.
影响因子：
0.9
作者：
Kaprio, Jaakko
通讯作者：
Kaprio, Jaakko
DOI：
10.1037/adb0000283
发表时间：
2017-08
期刊：
Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors
影响因子：
--
作者：
Waldron JS;Malone SM;McGue M;Iacono WG
通讯作者：
Iacono WG
影响因子：
7.4
作者：
Keyes, Katherine M.;McLaughlin, Katie A.;Demmer, Ryan T.;Cerda, Magdalena;Koenen, Karestan C.;Uddin, Monica;Galea, Sandro
通讯作者：
Galea, Sandro
影响因子：
5.8
作者：
Fan, Amy Z.;Russell, Marcia;Trevisan, Maurizio
通讯作者：
Trevisan, Maurizio