Relationships of Anxiety and Depression with Cardiovascular Health in Youth with Normal Weight to Severe Obesity.
Relationships of Anxiety and Depression with Cardiovascular Health in Youth with Normal Weight to Severe Obesity.
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DOI：
10.1016/j.jpeds.2018.03.059
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发表时间：
2018-08
期刊：
影响因子：
--
通讯作者：
Kelly AS
中科院分区：
文献类型：
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作者：
Gross AC;Kaizer AM;Ryder JR;Fox CK;Rudser KD;Dengel DR;Kelly AS
评估青少年抑郁和焦虑症状与心血管疾病危险因素和血管健康指标的关系。重度抑郁症和双相情感障碍被认为是青少年心血管疾病 (CVD) 的危险因素。参与者 (n=202) 是来自一项横断面研究的 8-18 岁青少年，该研究评估了各种 BMI 值（正常体重到严重肥胖）的心血管健康状况。 CVD风险测量包括血压、空腹血脂、血糖、胰岛素、颈动脉内膜中层厚度、顺应性和扩张性、肱动脉血流介导的扩张、颈动脉脉搏波速度、体脂百分比和代谢综合征聚类评分。焦虑和抑郁症状在儿童焦虑相关疾病筛查和流行病学研究中心儿童抑郁量表上自我报告。使用两组调整变量来评估有和没有焦虑或抑郁症状的人在 CVD 危险因素和血管结局方面的差异。第一组包括对坦纳阶段、性别和种族的调整；第二个还根据身体脂肪百分比进行了调整。在这两种模型中，焦虑与 CVD 危险因素或血管健康均没有显着相关性。抑郁症与高密度脂蛋白胆固醇、甘油三酯和代谢综合征聚类评分相关；当考虑身体脂肪百分比时，这些关系就会减弱。在考虑身体脂肪时，我们发现青少年自我报告的抑郁或焦虑症状与 CVD 危险因素或血管健康没有明确的关系。
To evaluate the relationships of depression and anxiety symptoms with CVD risk factors and measures of vascular health in youth. Major Depressive Disorder and Bipolar Disorder are considered cardiovascular disease (CVD) risk factors in youth. Participants (n=202) were 8-18-year-olds from a cross-sectional study evaluating cardiovascular health across a wide range of BMI values (normal weight to severe obesity). CVD risk measurement included blood pressure, fasting lipids, glucose, insulin, carotid artery intima-media thickness, compliance and distensibility, brachial artery flow-mediated dilation, carotid-radial artery pulse wave velocity, body fat percentage, and a metabolic syndrome cluster score. Anxiety and depression symptoms were self-reported on the Screen for Child Anxiety Related Disorders and Center of Epidemiological Studies Depression Scale for Children. Two sets of adjustment variables were used in evaluation of differences between those with and without anxiety or depression symptomatology for the CVD risk factor and vascular outcomes. The first set included adjustment for Tanner stage, sex, and race; the second additionally adjusted for percent body fat. Anxiety was not significantly associated with CVD risk factors or vascular health in either model. Depression was associated with HDL cholesterol, triglycerides, and metabolic syndrome cluster score; these relationships were attenuated when accounting for percent body fat. When accounting for body fat, we found no clear relationship of self-reported depression or anxiety symptoms with CVD risk factors or vascular health in youth.
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影响因子：
3.3
作者：
Palta P;Samuel LJ;Miller ER 3rd;Szanton SL
通讯作者：
Szanton SL
影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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DOI：
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发表时间：
2015-01-01
期刊：
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影响因子：
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作者：
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通讯作者：
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影响因子：
8
作者：
通讯作者：
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