COVID-19 vaccination refusal trends in Kenya over 2021.
COVID-19 vaccination refusal trends in Kenya over 2021.
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DOI：
10.1016/j.vaccine.2022.12.066
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发表时间：
2023-01-27
期刊：
影响因子：
5.5
通讯作者：
Waljee, Akbar K.
中科院分区：
文献类型：
--
作者：
Rego, Ryan T.;Kenney, Brooke;Ngugi, Anthony K.;Espira, Leon;Orwa, James;Siwo, Geoffrey H.;Sefa, Christabel;Shah, Jasmit;Weinheimer-Haus, Eileen;Delius, Antonia Johanna Sophie;Pape, Utz Johann;Irfan, Furqan B.;Abubakar, Amina;Shah, Reena;Wagner, Abram;Kolars, Joseph;Boulton, Matthew L.;Hofer, Timothy;Waljee, Akbar K.
拒绝接种加剧了全球COVID-19疫苗接种的不平等。东非没有研究检查拒绝接种疫苗的时间趋势，排除了解决拒绝问题。我们评估了肯尼亚随着时间的推移拒绝接种疫苗的情况，并描述了与拒绝接种疫苗的变化相关的因素。我们分析了肯尼亚快速反应电话调查（RRPS）的数据，这是一项代表肯尼亚人口（包括难民）的家庭队列调查。于2021年2月及10月测量了拒绝接种疫苗（定义为受访者表示，如果免费提供疫苗，他们将不会接受疫苗）的情况。绘制疫苗接种拒绝比例随时间的变化曲线。我们使用加权多变量逻辑回归分析了疫苗接种拒绝的因素，包括时间的相互作用。在11，569个家庭中，肯尼亚拒绝接种疫苗的比例从2021年2月的24%下降到2021年10月的9%。拒绝接种疫苗与接受过小学以上教育有关（-4.1 [-0.7，-8.9]个百分点差异（ppd））;与过去14天内出现COVID-19症状的人一起生活（−13.72[−8.9，−18.6]ppd）;在过去14天内有COVID-19症状（11.0[5.1，16.9]ppd）;以及不信任政府应对COVID-19（14.7[7.1，22.4]ppd）。与时间和难民身份和地理位置有显著的相互作用，与有COVID-19症状的人一起生活，有COVID-19症状，相信错误信息。肯尼亚拒绝接种疫苗的时间减少可能代表肯尼亚疫苗接种计划的重大进展和需要检查的可能教训。展望未来，仍有几个群体需要针对性地减少疫苗接种拒绝和提高疫苗接种公平性，包括教育水平较低的群体、最近出现COVID-19症状的群体、没有采取个人COVID-19缓解措施的群体、城市环境中的难民以及不信任政府的群体。政策和计划应侧重于减少这些人群拒绝接种疫苗的情况，研究应侧重于了解接种疫苗的障碍和动机。
Vaccination refusal exacerbates global COVID-19 vaccination inequities. No studies in East Africa have examined temporal trends in vaccination refusal, precluding addressing refusal. We assessed vaccine refusal over time in Kenya, and characterized factors associated with changes in vaccination refusal. We analyzed data from the Kenya Rapid Response Phone Survey (RRPS), a household cohort survey representative of the Kenyan population including refugees. Vaccination refusal (defined as the respondent stating they would not receive the vaccine if offered to them at no cost) was measured in February and October 2021. Proportions of vaccination refusal were plotted over time. We analyzed factors in vaccination refusal using a weighted multivariable logistic regression including interactions for time. Among 11,569 households, vaccination refusal in Kenya decreased from 24 % in February 2021 to 9 % in October 2021. Vaccination refusal was associated with having education beyond the primary level (−4.1[−0.7,−8.9] percentage point difference (ppd)); living with somebody who had symptoms of COVID-19 in the past 14 days (−13.72[−8.9,−18.6]ppd); having symptoms of COVID-19 in the past 14 days (11.0[5.1,16.9]ppd); and distrusting the government in responding to COVID-19 (14.7[7.1,22.4]ppd). There were significant interactions with time and: refugee status and geography, living with somebody with symptoms of COVID-19, having symptoms of COVID-19, and believing in misinformation. The temporal reduction in vaccination refusal in Kenya likely represents substantial strides by the Kenyan vaccination program and possible learnt lessons which require examination. Going forward, there are still several groups which need specific targeting to decrease vaccination refusal and improve vaccination equity, including those with lower levels of education, those with recent COVID-19 symptoms, those who do not practice personal COVID-19 mitigation measures, refugees in urban settings, and those who do not trust the government. Policy and program should focus on decreasing vaccination refusal in these populations, and research focus on understanding barriers and motivators for vaccination.
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影响因子：
4.5
作者：
Kumar D;Mathur M;Kumar N;Rana RK;Tiwary RC;Raghav PR;Kumar A;Kapoor N;Mathur M;Tanu T;Sethia S;Lahariya C
通讯作者：
Lahariya C
DOI：
10.1126/science.abk0414
发表时间：
2021-11-19
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Brand SPC;Ojal J;Aziza R;Were V;Okiro EA;Kombe IK;Mburu C;Ogero M;Agweyu A;Warimwe GM;Nyagwange J;Karanja H;Gitonga JN;Mugo D;Uyoga S;Adetifa IMO;Scott JAG;Otieno E;Murunga N;Otiende M;Ochola-Oyier LI;Agoti CN;Githinji G;Kasera K;Amoth P;Mwangangi M;Aman R;Ng'ang'a W;Tsofa B;Bejon P;Keeling MJ;Nokes DJ;Barasa E
通讯作者：
Barasa E
影响因子：
5.5
作者：
Trent M;Seale H;Chughtai AA;Salmon D;MacIntyre CR
通讯作者：
MacIntyre CR
影响因子：
15.1
作者：
Rego R;Watson S;Alam MAU;Abdullah SA;Yunus M;Alam IT;Chowdhury ASMHK;Haider SMA;Faruque A;Khan AI;Hofer T;Gill P;Islam MS;Lilford R
通讯作者：
Lilford R
影响因子：
7.8
作者：
Shah, Jasmit;Abeid, Abdulaziz;Sharma, Karishma;Manji, Soraiya;Nambafu, Jamila;Korom, Robert;Patel, Keya;Said, Mohamed;Mohamed, Mohamed Ali;Sood, Mohamed;Karani, Victor;Kamandi, Patrick;Kiptinness, Sarah;Rego, Ryan T.;Patel, Rajiv;Shah, Reena;Talib, Zohray;Ali, Sayed K.
通讯作者：
Ali, Sayed K.