Sensitivity of the hippocampus to objective but not subjective episodic memory judgments.

Sensitivity of the hippocampus to objective but not subjective episodic memory judgments.
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海马体对客观而非主观情景记忆判断的敏感性。

DOI:
10.1080/17588928.2022.2033713
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发表时间:
2022-07
影响因子:
2
通讯作者:
Rugg, Michael D.
Rugg, Michael D.
中科院分区:
医学4区
文献类型:
--
作者:
Thakral, Preston P.;Yu, Sarah S.;Rugg, Michael D.

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我们根据记忆测试项目是否引发主观回忆感或上下文信息的准确检索来评估海马体中的神经活动是否分离。我们重新分析了之前从一项研究中获得的数据集,其中参与者对每个测试项目做出了客观(空间背景的源记忆)和主观(记住-知道)判断。结果表明,海马体对检索到的上下文信息量完全敏感,因此,无论“记住/知道”状态如何,准确的源记忆判断比不准确的判断与更大的活动相关。这些发现进一步证明海马体对回忆的主观体验不敏感,但支持上下文信息的检索。
We assessed whether neural activity in the hippocampus dissociates according to whether memory test items elicit a subjective sense of recollection or accurate retrieval of contextual information. We reanalyzed a previously acquired dataset from a study in which participants made both objective (source memory for spatial context) and subjective (Remember-Know) judgments for each test item. Results indicated that the hippocampus was exclusively sensitive to the amount of contextual information retrieved, such that accurate source memory judgments were associated with greater activity than inaccurate judgments, regardless of Remember/Know status. The findings add to the evidence that the hippocampus is insensitive to the subjective experience of recollection, but supports retrieval of contextual information.
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