Dissociation of Recollection-Related Neural Activity in Ventral Lateral Parietal Cortex.

Dissociation of Recollection-Related Neural Activity in Ventral Lateral Parietal Cortex.
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DOI:
10.1080/17588928.2012.669363
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发表时间:
2012-09-01
影响因子:
2
通讯作者:
Rugg MD
Rugg MD
中科院分区:
医学4区
文献类型:
--
作者:
Yu SS;Johnson JD;Rugg MD

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当再认伴随回忆时,腹侧顶叶皮层的两个区域-角回和颞顶交界处(TPJ)-对再认记忆测试项目的fMRI反应增强。根据“情节缓冲”假说,腹顶叶回忆效应反映了维持或再现回忆信息的过程。然而,根据“注意力对记忆”的假设,这些效应反映了注意力重新定位到回忆的产品。本实验解决的问题,这些操作是否映射到角回和TPJ,分别。受试者在记忆测试中进行扫描,需要记住/知道/新的和源记忆判断,允许回忆的项目被分离的量的上下文信息回忆。角回的活动跟踪量的回忆信息,而在TPJ的活动增强赞同为回忆的项目,但不敏感的回忆的信息量。因此,这两个区域可能支持功能分离的过程。
fMRI responses to recognition memory test items in two regions of ventral lateral parietal cortex—the angular gyrus and temporo-parietal junction (TPJ)—are enhanced when recognition is accompanied by recollection. According to the ‘episodic buffer’ hypothesis, ventral parietal recollection effects reflect processes involved in maintaining or representing recollected information. According to the ‘attention to memory’ hypothesis, however, the effects reflect attentional re-orienting to the products of recollection. The present experiment addressed the question whether these operations map on to the angular gyrus and TPJ, respectively. Subjects were scanned during a memory test that required a Remember/Know/New and a source memory judgment, allowing recollected items to be segregated by amount of contextual information recollected. Angular gyrus activity tracked amount of recollected information, whereas activity in the TPJ was enhanced for items endorsed as recollected, but was insensitive to amount of information recollected. Thus, the two regions likely support functionally dissociable processes.
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