The aprosody of schizophrenia: Computationally derived acoustic phonetic underpinnings of monotone speech.
The aprosody of schizophrenia: Computationally derived acoustic phonetic underpinnings of monotone speech.
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DOI：
10.1016/j.schres.2018.01.007
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发表时间：
2018-07
影响因子：
4.5
通讯作者：
Covington MA
中科院分区：
文献类型：
--
作者：
Compton MT;Lunden A;Cleary SD;Pauselli L;Alolayan Y;Halpern B;Broussard B;Crisafio A;Capulong L;Balducci PM;Bernardini F;Covington MA
声学语音学方法在检查精神分裂症的某些症状时是有用的;我们使用这种方法来理解韵律的基础。我们假设，与对照组和没有临床评定的韵律失步的患者相比，韵律失步患者在以下方面表现出降低的变异性：音高（F0）、下颌/嘴开口和舌头高度（共振峰F1）、舌头前/后位置和/或嘴唇变圆（共振峰F2）以及强度/响度。从98名患者（包括25名临床评定为韵律的患者和29名无韵律的患者）和102名未受影响的对照组中获得录音语音，使用五项任务：一项描述绘画，两项基于通过问题引起的自发语音（任务2和3），以及两项基于阅读散文摘录（任务4和5）。我们比较了音高（F0），共振峰F1和F2，以及强度/响度的变化。关于音高变化，在未经调整的测试中，在任务3和任务4中，具有韵律的患者与对照组显著不同;对于任务5，在未经调整的测试和调整社会人口统计学的测试中，差异具有统计学显著性。对于F1的标准差（SD），在两个阅读任务的调整测试中观察到预期的模式。关于F2的SD，在所有任务的未调整测试中，有韵律的患者的值低于对照组;在调整测试中，在两个自发语音任务中观察到预期模式。这些发现可能代表了开发新方法的一步，用于使用声学语音参数测量和跟踪这种特定阴性症状的严重程度;这些工作与其他精神和神经系统疾病有关。
Acoustic phonetic methods are useful in examining some symptoms of schizophrenia; we used such methods to understand the underpinnings of aprosody. We hypothesized that, compared to controls and patients without clinically rated aprosody, patients with aprosody would exhibit reduced variability in: pitch (F0), jaw/mouth opening and tongue height (formant F1), tongue front/back position and/or lip rounding (formant F2), and intensity/loudness. Audiorecorded speech was obtained from 98 patients (including 25 with clinically rated aprosody and 29 without) and 102 unaffected controls using five tasks: one describing a drawing, two based on spontaneous speech elicited through a question (Tasks 2 and 3), and two based on reading prose excerpts (Tasks 4 and 5). We compared groups on variation in pitch (F0), formant F1 and F2, and intensity/loudness. Regarding pitch variation, in unadjusted tests, patients with aprosody differed significantly from controls in Tasks 3 and 4; for Task 5, the difference was statistically significant in both unadjusted tests and those adjusted for sociodemographics. For the standard deviation (SD) of F1, the expected pattern was observed in the two reading tasks in adjusted tests. Regarding SD of F2, patients with aprosody had lower values than controls in unadjusted tests across all tasks; in adjusted tests the expected pattern was observed in the two spontaneous speech tasks. Findings could represent a step toward developing new methods for measuring and tracking the severity of this specific negative symptom using acoustic phonetic parameters; such work is relevant to other psychiatric and neurological disorders.
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