Distinctive patterns of interdigestive motility at the canine ileocolonic junction
Distinctive patterns of interdigestive motility at the canine ileocolonic junction
复制标题
犬回结肠交界处消化间运动的独特模式
DOI:
10.1016/0016-5085(84)90077-5
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发表时间:
1984
期刊:
影响因子:
29.4
通讯作者:
S. Phillips
中科院分区:
文献类型:
--
作者:
E. Quigley;S. Phillips
Studies of interdigestive motor activity in the distal ileum, ileocolonic sphincter, and proximal colon were performed in two groups of dogs: (i) in those with ileocolonic loops that maintained neuromuscular continuity with the proximal intestine, we used an intraluminal side-hole assembly; (ii) in those with intact bowel, we attached extraluminal strain gauge transducers. Both groups of animals were equipped also with serosal electrodes. Positioning of motor sensors could be defined accurately by (a) a clear separation of rhythmic frequencies between those of the distal ileum (mean 10.8 cycles/min) and proximal colon (mean 6.2 cycles/min) and (b) the characteristic motor patterns of the ileocolonic sphincter. Analysis of motor activity in the segment demonstrated four distinct patterns: (i) irregular, apparently random phasic waves, (ii) rhythmic bursts of contractions corresponding to phase III of the migrating motor complex, (iii) other slowly propagated bursts of rhythmic activity (mean duration 3.6 min) recurring on average every 10 min, and (iv) single, prolonged (mean duration 16.7 s), high amplitude (mean 271 cmH2O) waves that propagated rapidly (“prolonged propagated contractions”). The latter two patterns appear unique to, or unusually prominent in, this region. A high degree of motor coordination between the distal ileum, ileocolonic sphincter, and proximal colon was also recognized. Thus, the patterns of motor activity suggest a specialized function for the distal 30 cm of ileum, the ileocolonic sphincter, and the proximal colon. These unique and coordinated patterns of motility deserve further exploration, especially in relation to ileocolonic transit and actions of the sphincter as a barrier to colo-ileal reflux.
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DOI:
10.1172/jci110761
发表时间:
1983
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
Toouli,J;Dodds,WJ;Honda,R;Sarna,S;Hogan,WJ;Komarowski,RA;Linehan,JH;Arndorfer,RC
通讯作者:
Arndorfer,RC
影响因子:
29.4
作者:
Quigley,EM;Phillips,SF;Dent,J;Taylor,BM
通讯作者:
Taylor,BM
DOI:
10.1152/ajpgi.1981.240.2.g147
发表时间:
1981
期刊:
The American journal of physiology
影响因子:
--
作者:
Weems,WA;Seygal,GE
通讯作者:
Seygal,GE
DOI:
10.1152/ajpgi.1981.241.3.g222
发表时间:
1981
期刊:
The American journal of physiology
影响因子:
--
作者:
Cardwell,BA;Rubin,MR;SnapeJr,WJ;Cohen,S
通讯作者:
Cohen,S
DOI:
10.1172/jci110476
发表时间:
1982
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
Ouyang,A;Clain,CJ;SnapeJr,WJ;Cohen,S
通讯作者:
Cohen,S