Distinctive patterns of interdigestive motility at the canine ileocolonic junction

Distinctive patterns of interdigestive motility at the canine ileocolonic junction
复制标题

犬回结肠交界处消化间运动的独特模式

DOI:
10.1016/0016-5085(84)90077-5
复制
发表时间:
1984
期刊:
影响因子:
29.4
通讯作者:
S. Phillips
S. Phillips
中科院分区:
医学1区
文献类型:
--
作者:
E. Quigley;S. Phillips

文献摘要

参考文献

被引文献

相似文献

在两组犬中进行了远端回肠、回结肠括约肌和近端结肠的消化间期运动活动研究:(i)在具有与近端肠保持神经肌肉连续性的回结肠环的犬中,我们使用了腔内侧孔组件;(ii)在具有完整肠的犬中,我们连接了腔外应变计传感器。两组动物也配备了serovirus电极。运动传感器的定位可以通过以下方式准确定义:(a)远端回肠(平均10.8周期/min)和近端结肠(平均6.2周期/min)之间的节律频率的明确分离,以及(B)回结肠括约肌的特征运动模式。对该段运动活动的分析表明了四种不同的模式:(i)不规则的,明显随机的相位波,(ii)与移行运动复合体的III相对应的收缩的节律性爆发,(iii)其他缓慢传播的节律性活动爆发(平均持续时间3.6分钟)平均每10分钟复发一次,和(iv)单次,延长(平均持续时间16.7 s),高振幅(平均271 cmH 2 O)波快速传播(“延长的传播性收缩”)。后两种模式似乎是该地区所特有的,或者说是异常突出的。远端回肠、回结肠括约肌和近端结肠之间的运动协调性也很高。因此,运动活动的模式表明回肠远端30 cm、回结肠括约肌和近端结肠具有专门的功能。这些独特而协调的运动模式值得进一步探讨,特别是在回结肠运输和作为结肠回肠反流屏障的括约肌的作用。
Studies of interdigestive motor activity in the distal ileum, ileocolonic sphincter, and proximal colon were performed in two groups of dogs: (i) in those with ileocolonic loops that maintained neuromuscular continuity with the proximal intestine, we used an intraluminal side-hole assembly; (ii) in those with intact bowel, we attached extraluminal strain gauge transducers. Both groups of animals were equipped also with serosal electrodes. Positioning of motor sensors could be defined accurately by (a) a clear separation of rhythmic frequencies between those of the distal ileum (mean 10.8 cycles/min) and proximal colon (mean 6.2 cycles/min) and (b) the characteristic motor patterns of the ileocolonic sphincter. Analysis of motor activity in the segment demonstrated four distinct patterns: (i) irregular, apparently random phasic waves, (ii) rhythmic bursts of contractions corresponding to phase III of the migrating motor complex, (iii) other slowly propagated bursts of rhythmic activity (mean duration 3.6 min) recurring on average every 10 min, and (iv) single, prolonged (mean duration 16.7 s), high amplitude (mean 271 cmH2O) waves that propagated rapidly (“prolonged propagated contractions”). The latter two patterns appear unique to, or unusually prominent in, this region. A high degree of motor coordination between the distal ileum, ileocolonic sphincter, and proximal colon was also recognized. Thus, the patterns of motor activity suggest a specialized function for the distal 30 cm of ileum, the ileocolonic sphincter, and the proximal colon. These unique and coordinated patterns of motility deserve further exploration, especially in relation to ileocolonic transit and actions of the sphincter as a barrier to colo-ileal reflux.
负鼠奥迪括约肌的运动功能。
DOI: 10.1172/jci110761
发表时间: 1983
期刊: The Journal of clinical investigation
影响因子: --
作者:
Toouli,J;Dodds,WJ;Honda,R;Sarna,S;Hogan,WJ;Komarowski,RA;Linehan,JH;Arndorfer,RC
通讯作者: Arndorfer,RC
DOI: --
发表时间: 1983
期刊: Gastroenterology
影响因子: 29.4
作者:
Quigley,EM;Phillips,SF;Dent,J;Taylor,BM
通讯作者: Taylor,BM
在需要静水力工作的条件下,猫肠段进行流体推进。
DOI: 10.1152/ajpgi.1981.240.2.g147
发表时间: 1981
期刊: The American journal of physiology
影响因子: --
作者:
Weems,WA;Seygal,GE
通讯作者: Seygal,GE
猫回盲部括约肌的特性。
DOI: 10.1152/ajpgi.1981.241.3.g222
发表时间: 1981
期刊: The American journal of physiology
影响因子: --
作者:
Cardwell,BA;Rubin,MR;SnapeJr,WJ;Cohen,S
通讯作者: Cohen,S
DOI: 10.1172/jci110476
发表时间: 1982
期刊: The Journal of clinical investigation
影响因子: --
作者:
Ouyang,A;Clain,CJ;SnapeJr,WJ;Cohen,S
通讯作者: Cohen,S