COVID‐19 vaccination and decreased death rates: A county‐level study in Pennsylvania

COVID‐19 vaccination and decreased death rates: A county‐level study in Pennsylvania
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COVID-19 疫苗接种与死亡率降低:宾夕法尼亚州的一项县级研究

DOI:
10.1002/jmv.28883
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发表时间:
2023
影响因子:
12.7
通讯作者:
Savitz, Ryan
Savitz, Ryan
中科院分区:
医学3区
文献类型:
--
作者:
Ramunno, Maria;Savitz, Ryan

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在本文中,我们研究了接种COVID-19疫苗与COVID-19死亡率和COVID-19传播率之间的关系。我们的目标是确定疫苗接种是否与地方一级的死亡和/或疾病传播减少有关。是项分析于美利坚合众国宾夕法尼亚州的县层面进行,数据于二零二二年上半年从宾夕法尼亚州的Covid Dashboard(COVID-19 Data for Pennsylvania(pa. gov))收集。这项研究发现,疫苗在预防冠状病毒死亡方面非常有效,即使在疫苗和流行变种之间存在不匹配的时候。具体而言,发现疫苗接种率增加1%对应于死亡率降低0.751%(95%置信区间[0.236%,1.266%])。鉴于在此期间,所使用的疫苗并不是专门针对当时的常见变异,我们发现县级疾病传播和疫苗接种率之间没有统计学显著关系。这些结果支持了世界各地先前的研究结果,即新冠疫苗接种在预防疾病死亡方面非常有效。即使在疫苗设计与流行毒株不匹配的时期,也发现接种疫苗可以降低死亡率。因此,改善全球疫苗供应对于取得必要成果至关重要。
In this paper we examine the relationship between vaccination against COVID‐19 and both the death rate from COVID‐19 and the rate of COVID‐19 spread. Our goal is determine if vaccination is associated with reduced death and/or spread of disease at the local level. This analysis was conducted at the county level in the state of Pennsylvania, United States of America, with data that were collected during the first half of 2022 from the state of Pennsylvania's Covid Dashboard (COVID‐19 Data for Pennsylvania (pa.gov). This study finds the vaccines to be highly effective in preventing death from Corona virus, even at a time when there was a mismatch between the vaccines and the prevalent variants. Specifically, a 1% increase in vaccination rate was found to correspond to a 0.751% decrease in death rate (95% confidence interval [0.236%, 1.266%]). Given that, during this time period, the vaccines being used were not geared specifically toward the common variants at that time, we found no statistically significant relationship between disease spread and vaccination rate at the county level. These results support previous findings from across the world that Covid vaccination is highly efficacious in preventing death from the disease. Even during a time when vaccine design was not optimally matched with the prevailing strains, vaccination was found to reduce death rate. Hence, improving global vaccine availability is vitally important, to achieve necessary outcomes.
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发表时间: 2020-07-29
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发表时间: 2022
期刊: COMMUNICATIONS MEDICINE
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影响因子: 7.2
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