Irritability uniquely predicts prefrontal cortex activation during preschool inhibitory control among all temperament domains: A LASSO approach.
Irritability uniquely predicts prefrontal cortex activation during preschool inhibitory control among all temperament domains: A LASSO approach.
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DOI：
10.1016/j.neuroimage.2018.09.023
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发表时间：
2019-01-01
期刊：
影响因子：
5.7
通讯作者：
Perlman SB
中科院分区：
文献类型：
--
作者：
Fishburn FA;Hlutkowsky CO;Bemis LM;Huppert TJ;Wakschlag LS;Perlman SB
气质被定义为情绪、运动和注意过程的反应性和调节的个体差异，已被证明影响学龄前阶段(4-5岁)的情绪和认知发展。虽然之前已经研究了气质和神经活动之间的关系，但这些研究通常是对个别气质维度进行特别选择。由于不同气质维度之间存在显著的相关性，目前尚不清楚这些发现是否会在同时分析所有气质维度时重复。采用功能性近红外光谱(FNIRS)技术，对118名4-5岁儿童(N=118)进行Go/No-Go任务，以评估抑制控制期间前额叶皮质的激活情况。儿童行为问卷(CBQ)定义的所有15个气质领域与PFC激活之间的关系通过套索回归的自动特征选择来评估。结果表明，只有愤怒/挫折维度对抑制控制任务中的激活有预测作用。这些发现支持了先前关于执行功能中易怒和前额叶激活之间的关系的工作，并通过证明气质维度之间的激活-激惹关系的特殊性来扩展这些发现。
Temperament, defined as individual variation in the reactivity and regulation of emotional, motor, and attentional processes, has been shown to influence emotional and cognitive development during the preschool period (ages 4–5). While relationships between temperament and neural activity have been investigated previously, these have typically investigated individual temperament dimensions selected ad hoc. Since significant correlations exist between various temperament dimensions, it remains unclear whether these findings would replicate while analyzing all temperament dimensions simultaneously. Using functional near infrared spectroscopy (fNIRS), 4–5-year-old children (N=118) were administered a Go/No-Go task to assess prefrontal cortex activation during inhibitory control. The relationship between PFC activation and all 15 temperament domains defined by the Children’s Behavior Questionnaire (CBQ) was assessed using automatic feature selection via LASSO regression. Results indicate that only the Anger/Frustration dimension was predictive of activation during the inhibitory control task. These findings support previous work showing relationships between irritability and prefrontal activation during executive function and extend those findings by demonstrating the specificity of the activation-irritability relationship among temperament dimensions.
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DOI：
10.1073/pnas.96.14.8301
发表时间：
1999-07-06
影响因子：
11.1
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HOCHBERG, Y
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SASAKI, K
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DOI：
10.1073/pnas.1108561108
发表时间：
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影响因子：
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