A role for cognitive rehabilitation in increasing the effectiveness of treatment for alcohol use disorders.
A role for cognitive rehabilitation in increasing the effectiveness of treatment for alcohol use disorders.
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DOI：
10.1007/s11065-013-9228-3
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发表时间：
2013-03
影响因子：
5.8
通讯作者：
Nguyen, Tam T.
中科院分区：
文献类型：
--
作者：
Bates, Marsha E.;Buckman, Jennifer F.;Nguyen, Tam T.
关键词：
神经认知障碍在寻求酒精使用障碍（AUD）治疗的人中很普遍。这些损伤及其生理、社会、心理和职业后果的严重程度因人而异，很像创伤性脑损伤造成的后果;然而，由于其发病过程较慢，酒精相关的认知障碍往往在治疗环境内外都被忽视。有证据表明，认知障碍可能通过其对治疗过程的影响而阻碍治疗目标的实现。虽然酒精相关的认知障碍的一些恢复通常发生在停止饮酒后（时间依赖性恢复），但恢复的速度和程度在认知领域和个体之间是可变的。在科学兴趣长期中断之后，新一代研究旨在通过直接促进认知恢复（经验依赖性恢复）来促进治疗过程并改善AUD治疗结果。本综述更新了与AUD相关的认知和脑损伤的性质和过程的知识，包括青少年AUD的认知影响。我们总结了认知障碍与治疗结果之间的间接和调节关系的现有证据，并讨论了脑行为关系概念框架的进展如何推动包括认知补救技术在内的新型AUD干预措施的发展。新出现的证据表明，这些干预措施可以有效促进AUD和其他物质使用障碍患者的认知恢复，并可能提高AUD治疗的疗效。最后，基于认知科学，神经生理学和神经科学研究的转化方法被认为是有效治疗发展的未来方向，包括认知康复。
Neurocognitive impairments are prevalent in persons seeking treatment for alcohol use disorders (AUDs). These impairments and their physical, social, psychological and occupational consequences vary in severity across persons, much like those resulting from traumatic brain injury; however, due to their slower course of onset, alcohol-related cognitive impairments are often overlooked both within and outside of the treatment setting. Evidence suggests that cognitive impairments can impede treatment goals through their effects on treatment processes. Although some recovery of alcohol-related cognitive impairments often occurs after cessation of drinking (time-dependent recovery), the rate and extent of recovery is variable across cognitive domains and individuals. Following a long hiatus in scientific interest, a new generation of research aims to facilitate treatment process and improve AUD treatment outcomes by directly promoting cognitive recovery (experience-dependent recovery). This review updates knowledge about the nature and course of cognitive and brain impairments associated with AUD, including cognitive effects of adolescent AUD. We summarize current evidence for indirect and moderating relationships of cognitive impairment to treatment outcome, and discuss how advances in conceptual frameworks of brain-behavior relationships are fueling the development of novel AUD interventions that include techniques for cognitive remediation. Emerging evidence suggests that such interventions can be effective in promoting cognitive recovery in persons with AUD and other substance use disorders, and potentially increasing the efficacy of AUD treatments. Finally, translational approaches based on cognitive science, neurophysiology, and neuroscience research are considered as promising future directions for effective treatment development that includes cognitive rehabilitation.
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影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
影响因子：
3.3
作者：
Anderson ML;Nokia MS;Govindaraju KP;Shors TJ
通讯作者：
Shors TJ
影响因子：
3.4
作者：
Amlung M;Sweet LH;Acker J;Brown CL;MacKillop J
通讯作者：
MacKillop J
DOI：
10.1097/01.alc.0000156131.88125.2a
发表时间：
2005-03-01
期刊：
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH
影响因子：
--
作者：
Bates, ME;Voelbel, GT;Barry, D
通讯作者：
Barry, D
影响因子：
17.7
作者：
Bjork, JM;Grant, SJ;Hommer, DW
通讯作者：
Hommer, DW