Recent Fast Food Consumption and Bisphenol A and Phthalates Exposures among the U.S. Population in NHANES, 2003-2010.
Recent Fast Food Consumption and Bisphenol A and Phthalates Exposures among the U.S. Population in NHANES, 2003-2010.
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DOI：
10.1289/ehp.1510803
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发表时间：
2016-10
影响因子：
10.4
通讯作者：
Mitro SD
中科院分区：
文献类型：
--
作者：
Zota AR;Phillips CA;Mitro SD
邻苯二甲酸酯和双酚A（BPA）是广泛使用的工业化学品，可能对人类健康产生不利影响。人体接触是普遍存在的，可通过饮食发生，包括食用加工或包装食品。研究美国人群近期快餐摄入量与BPA和邻苯二甲酸二（2-乙基己基）酯（DEHP m）和邻苯二甲酸二异壬酯（DiNPm）的尿液代谢物之间的关联。我们结合了来自国家健康和营养调查（NHANES 2003-2010）的8，877名参与者的数据。使用24小时饮食回忆数据，我们量化了：a）快餐摄入量[来自快餐的总能量摄入量（TEI）的百分比]; B）快餐衍生的脂肪摄入量（来自快餐中脂肪的TEI百分比）;以及c）按食物组（乳制品，鸡蛋，谷物，肉类和其他）的快餐摄入量。我们用多元线性回归分析了饮食暴露和尿中化学物质浓度之间的关系。我们观察到的证据表明，快餐摄入量和邻苯二甲酸酯暴露之间存在正的剂量反应关系（p趋势< 0.0001）但不含BPA;高消费参与者（≥ 34.9%TEI来自快餐）的人群中，DEHP和DiNPm的水平分别比非消费者高23.8%（95%CI：11.9%，36.9%）和39.0%（95%CI：21.9%，58.5%）。快餐来源的脂肪摄入量也与DEHPm和DiNPm呈正相关（p趋势< 0.0001）。在调整其他食物组后，DEHPm与谷物和其他摄入量相关，DiNPm与肉类和谷物摄入量相关。快餐可能是接触DEHP和DiNP的来源。这些结果，如果得到证实，可以告知个人和监管暴露减少策略。Zota AR，菲利普斯CA，Mitro SD. 2016. 2003-2010年NHANES中美国人口近期快餐消费与双酚A和邻苯二甲酸酯暴露环境健康展望124：1521-1528; http：dx.doi.org/10.1289/ehp.1510803
Phthalates and bisphenol A (BPA) are widely used industrial chemicals that may adversely impact human health. Human exposure is ubiquitous and can occur through diet, including consumption of processed or packaged food. To examine associations between recent fast food intake and BPA and urinary metabolites of di(2-ethylhexyl) phthalate (ΣDEHPm) and diisononyl phthalate (DiNPm) among the U.S. population. We combined data on 8,877 participants from the National Health and Nutrition Examination Survey (NHANES 2003–2010). Using 24-hr dietary recall data, we quantified: a) fast food intake [percent of total energy intake (TEI) from fast food]; b) fast food-derived fat intake (percent of TEI from fat in fast food); and c) fast food intake by food group (dairy, eggs, grains, meat, and other). We examined associations between dietary exposures and urinary chemical concentrations using multivariate linear regression. We observed evidence of a positive, dose–response relationship between fast food intake and exposure to phthalates (p-trend < 0.0001) but not BPA; participants with high consumption (≥ 34.9% TEI from fast food) had 23.8% (95% CI: 11.9%, 36.9%) and 39.0% (95% CI: 21.9%, 58.5%) higher levels of ΣDEHPm and DiNPm, respectively, than nonconsumers. Fast food-derived fat intake was also positively associated with ΣDEHPm and DiNPm (p-trend < 0.0001). After adjusting for other food groups, ΣDEHPm was associated with grain and other intake, and DiNPm was associated with meat and grain intake. Fast food may be a source of exposure to DEHP and DiNP. These results, if confirmed, could inform individual and regulatory exposure reduction strategies. Zota AR, Phillips CA, Mitro SD. 2016. Recent fast food consumption and bisphenol A and phthalates exposures among the U.S. population in NHANES, 2003–2010. Environ Health Perspect 124:1521–1528; http://dx.doi.org/10.1289/ehp.1510803
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影响因子：
10.4
作者：
Schecter A;Lorber M;Guo Y;Wu Q;Yun SH;Kannan K;Hommel M;Imran N;Hynan LS;Cheng D;Colacino JA;Birnbaum LS
通讯作者：
Birnbaum LS
影响因子：
10.4
作者：
Rudel RA;Gray JM;Engel CL;Rawsthorne TW;Dodson RE;Ackerman JM;Rizzo J;Nudelman JL;Brody JG
通讯作者：
Brody JG
影响因子：
3.6
作者：
Braun JM;Sathyanarayana S;Hauser R
通讯作者：
Hauser R
DOI：
10.1078/1438-4639-00270
发表时间：
2004-01-01
影响因子：
6
作者：
Koch, HM;Drexler, H;Angerer, J
通讯作者：
Angerer, J
影响因子：
6.1
作者：
Cirillo, Teresa;Fasano, Evelina;Cocchieri, Renata Amodio
通讯作者：
Cocchieri, Renata Amodio