Sheep scab: comparison of spatial and temporal patterns determined by clinical diagnosis or ELISA.
Sheep scab: comparison of spatial and temporal patterns determined by clinical diagnosis or ELISA.
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DOI：
10.1186/s13071-022-05564-5
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发表时间：
2022-11-11
影响因子：
3.2
通讯作者：
中科院分区：
文献类型：
--
作者：
绵羊痒螨（绵羊疥疮）是由对螨的过敏原诱导的超敏反应引起的传染病。在许多产羊国家，寄生虫感染导致临床疾病、经济损失和福利问题。本研究的目的是比较邻近农场羊疥疮的流行率和空间格局，使用自我报告的临床爆发史（2012-2020年）和酶联免疫吸附试验的血清学检测（2021/2022）。研究中包括的农场位于英格兰北部、中部和西南部三个已知的高结痂率地区。总共有254个农场完成了问卷调查，提供了农场的临床结痂史，并提交了ELISA血清学检测结果。根据临床诊断，2020年有17. 4%（±置信区间[CI]：4. 6%; n = 48）的农场报告了结痂疫情; 2021/2022年有25. 6%（± 5. 5%; n = 65）的农场通过ELISA诊断出结痂。将自报的临床结痂病例与ELISA检测结果进行比较，发现一组农场（n = 52）在2020年没有报告结痂，或在某些情况下在过去8年没有报告结痂（n = 20），但其鸡群在2021/2022年仍然呈血清阳性。少数羊群，特别是那些在英格兰北部使用普通放牧的羊群，在那里处理是不频繁的，通常包括不太敏感的绵羊品种，可能有持续的结痂感染，通常无法通过临床检查发现。这些数据突出了血清学检测的优势，以确定暴露于结痂的鸡群中的临床症状是不容易发现的。
Ovine psoroptic mange (sheep scab) is an infectious condition caused by an allergen-induced hypersensitivity response to the mite Psoroptes ovis. Infestation results in clinical disease, economic loss and welfare issues in many sheep-producing countries. The aim of this study was to compare the prevalence and spatial pattern of sheep scab on contiguous farms, using both self-reported clinical outbreak history (2012–2020) and serological testing with an enzyme-linked immunosorbent assay (2021/2022). Farms included in the study were located in three regions of known high scab prevalence in North, Central and Southwest England. In total, 254 farms completed both a questionnaire, which provided the clinical scab history of the farm, and submitted results of serological testing with the ELISA. A scab outbreak was reported by 17.4% (± confidence interval [CI]: 4.6%; n = 48) of farms in 2020 based on clinical diagnosis; scab was diagnosed by the ELISA on 25.6% (± 5.5%; n = 65) of farms in 2021/2022. Comparison of self-reported clinical scab cases with the ELISA test results identified a group of farms (n = 52) that did not report scab in 2020, or in some cases did not report having scab over the previous 8 years (n = 20), but whose flocks were nevertheless seropositive in 2021/2022. A small number of flocks, particularly those using common grazings in North England, where handling is infrequent, often comprising less susceptible sheep breeds, may have persistent scab infestations that are generally undetected by clinical inspection. The data highlight the advantages of serological testing to identify exposure to scab in flocks where clinical signs are less easily detected.
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影响因子：
2
作者：
Davies, Tilman M.;Marshall, Jonathan C.;Hazelton, Martin L.
通讯作者：
Hazelton, Martin L.
影响因子：
2
作者：
Davies, Tilman M.;Hazelton, Martin L.
通讯作者：
Hazelton, Martin L.
影响因子：
2.6
作者：
Rose, Hannah;Wall, Richard
通讯作者：
Wall, Richard
影响因子：
3.3
作者：
Nunn, Francesca G.;Burgess, Stewart T. G.;Huntley, John F.
通讯作者：
Huntley, John F.
影响因子：
2.6
作者：
Sturgess-Osborne, C.;Burgess, S.;Wall, R.
通讯作者：
Wall, R.