A virologic survey of patients admitted to a critical care unit for acute cardiorespiratory failure.
A virologic survey of patients admitted to a critical care unit for acute cardiorespiratory failure.
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DOI：
10.1007/s00134-005-2861-4
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发表时间：
2006-01
影响因子：
38.9
通讯作者：
Offenstadt G
中科院分区：
文献类型：
--
作者：
Carrat F;Leruez-Ville M;Tonnellier M;Baudel JL;Deshayes J;Meyer P;Maury E;Galimand J;Rouzioux C;Offenstadt G
记录因急性心肺衰竭而入住重症监护室的慢性心脏或肺部疾病患者中呼吸道病毒感染的患病率。该研究在连续两个冬天的重症监护室进行。所有因急性呼吸衰竭或心力衰竭而入院的患者均入组。采集鼻拭子进行流感病毒、呼吸道合胞病毒（RSV）、偏肺病毒、鼻病毒和冠状病毒的聚合酶链反应（PCR）检测。122例患者入组。他们的平均年龄为69岁; 42%的患者为女性;入院时的新简化急性生理学评分（SAPS II）评分为35.6; 94%的患者患有急性呼吸衰竭，14%的患者在入院前报告了“流感样”疾病，11%的患者在该单位死亡。21名患者（17%）的呼吸道病毒检测呈阳性。每千人的阳性率为流感病毒66、RSV 49、鼻病毒33、偏肺病毒16和冠状病毒8。病毒学结果和临床结果之间没有发现联系。流感病毒阳性率与社区流感样疾病的发病率之间存在密切联系（p=0.017）。这些结果表明，呼吸道病毒感染，特别是流行期间的流感病毒感染，在急性心肺衰竭住院患者中很常见。
To document the prevalence of respiratory virus infections in patients with chronic cardiac or pulmonary disorders admitted to a critical care unit for acute cardiorespiratory failure. The study took place in a critical care unit during two consecutive winters. All patients admitted to the unit for acute respiratory or cardiac failure were enrolled. A nasal swab was taken for polymerase chain reaction (PCR) detection of influenza virus, respiratory syncytial virus (RSV), metapneumovirus, rhinovirus, and coronavirus. One hundred twenty-two patients were enrolled. Their mean age was 69 years; 42% of the patients were female; the new simplified acute physiology score (SAPS II) score on admission was 35.6; 94% of patients had acute respiratory failure, 14% reported “influenza-like” illness before admission, and 11% of patients died in the unit. Twenty-one patients (17%) tested positive for a respiratory virus. The per-1,000 positivity rates were influenza virus 66, RSV 49, rhinovirus 33, metapneumovirus 16, and coronavirus 8. No link was found between virologic results and clinical outcome. A strong link was found between the rate of influenza virus positivity and the incidence of flu-like illness in the community (p=0.017). These results show that respiratory virus infection—particularly influenza virus infection during epidemic periods—is common among patients hospitalized for acute cardiorespiratory failure.
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影响因子：
9.4
作者：
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通讯作者：
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作者：
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作者：
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通讯作者：
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作者：
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通讯作者：
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