The impact of oat structure and β-glucan on in vitro lipid digestion.
The impact of oat structure and β-glucan on in vitro lipid digestion.
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DOI：
10.1016/j.jff.2017.09.011
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发表时间：
2017-11
影响因子：
5.6
通讯作者：
Wilde PJ
中科院分区：
文献类型：
--
作者：
Grundy MML;Quint J;Rieder A;Ballance S;Dreiss CA;Cross KL;Gray R;Bajka BH;Butterworth PJ;Ellis PR;Wilde PJ
燕麦β-葡聚糖对脂质消化的影响取决于聚合物的递送形式。燕麦组织的结构是决定其对（体外）脂质消化影响的重要因素。消化过程中燕麦细胞壁的β-葡聚糖释放不完全。燕麦的加工影响脂解的速率和程度。粘度不是影响脂解的唯一因素。燕麦β-葡聚糖已被证明在影响脂质和胆固醇代谢方面发挥积极作用。然而，这些有益效果背后的机制尚未完全了解。目前的工作目的是研究燕麦β-葡聚糖降低胆固醇作用背后的一些可能机制，以及燕麦加工如何调节脂解。在胃肠道消化过程中，研究了β-葡聚糖的释放以及在存在不同来源的燕麦β-葡聚糖的情况下测量的脂解速率和程度。在消化过程中，只有一小部分原始β-葡聚糖含量被释放出来。燕麦片和燕麦粉似乎比纯化的β-葡聚糖对脂解的影响更显著。这些发现表明，β-葡聚糖的积极作用可能涉及复杂的过程和与食物基质的相互作用。这项工作还强调了考虑食物的结构和物理化学性质的重要性，而不仅仅是营养成分。
The effect of oat β-glucan on lipid digestion relies on the delivery form of the polymer. The structure of oat tissue is an important factor for determining its influence on (in vitro) lipid digestion. β-glucan release from oat cell walls during digestion was not complete. Processing of oats affects the rate and extent of lipolysis. Viscosity is not the only factor affecting lipolysis. Oat β-glucan has been shown to play a positive role in influencing lipid and cholesterol metabolism. However, the mechanisms behind these beneficial effects are not fully understood. The purpose of the current work was to investigate some of the possible mechanisms behind the cholesterol lowering effect of oat β-glucan, and how processing of oat modulates lipolysis. β-Glucan release, and the rate and extent of lipolysis measured in the presence of different sources of oat β-glucan, were investigated during gastrointestinal digestion. Only a fraction of the original β-glucan content was released during digestion. Oat flakes and flour appeared to have a more significant effect on lipolysis than purified β-glucan. These findings show that the positive action of β-glucan is likely to involve complex processes and interactions with the food matrix. This work also highlights the importance of considering the structure and physicochemical properties of foods, and not just the nutrient content.
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杏仁的细胞壁封装对体外十二指肠脂解的影响。
影响因子：
8.8
作者：
Grundy MM;Wilde PJ;Butterworth PJ;Gray R;Ellis PR
通讯作者：
Ellis PR
影响因子：
8.8
作者：
Gunness, Purnima;Flanagan, Bernadine M.;Gidley, Michael J.
通讯作者：
Gidley, Michael J.
影响因子：
10.7
作者：
Moschakis, Thomas;Lazaridou, Athina;Biliaderis, Costas G.
通讯作者：
Biliaderis, Costas G.
DOI：
10.3945/ajcn.114.106203
发表时间：
2015-10
期刊：
The American journal of clinical nutrition
影响因子：
--
作者：
Edwards CH;Grundy MM;Grassby T;Vasilopoulou D;Frost GS;Butterworth PJ;Berry SE;Sanderson J;Ellis PR
通讯作者：
Ellis PR
影响因子：
15.6
作者：
Jenkins, P;Snowden, M
通讯作者：
Snowden, M