Simultaneous Transcranial Magnetic Stimulation and Functional Magnetic Resonance Imaging: Aspects of Technical Implementation.

Simultaneous Transcranial Magnetic Stimulation and Functional Magnetic Resonance Imaging: Aspects of Technical Implementation.
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同步经颅磁刺激和功能磁共振成像:技术实施方面。

DOI:
10.3389/fnins.2020.554714
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发表时间:
2020
影响因子:
4.3
通讯作者:
Yang Y
Yang Y
中科院分区:
医学2区
文献类型:
--
作者:
Caparelli EC;Zhai T;Yang Y

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同时经颅磁刺激 (TMS) 和功能磁共振成像 (fMRI) 提供了一个独特的机会,可以非侵入性地刺激大脑回路,同时监测大脑活动的变化。然而,为了利用这种多模式技术,需要考虑/解决一些技术问题。在这项工作中,我们评估了与这种多模态工具的设置和使用相关的技术问题,例如大型单通道射频 (rf) 线圈的使用,以及 TMS 在与平面回波成像 (EPI) 序列交织时引起的伪影。我们证明,使用该射频线圈可以实现良好的图像质量,并且采用轴向成像定向以及 TMS 脉冲和成像采集之间 100 ms 的安全间隔是消除在 3-T MRI 扫描仪中使用组合 TMS-fMRI 技术时潜在图像伪影的合适组合。
The simultaneous transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI) offers a unique opportunity to non-invasively stimulate brain circuits while simultaneously monitoring changes in brain activity. However, to take advantage of this multimodal technique, some technical issues need to be considered/addressed. In this work, we evaluated technical issues associated with the setup and utilization of this multimodal tool, such as the use of a large single-channel radio frequency (rf) coil, and the artifacts induced by TMS when interleaved with the echo-planar imaging (EPI) sequence. We demonstrated that good image quality can be achieved with this rf coil and that the adoption of axial imaging orientation in conjunction with a safe interval of 100 ms, between the TMS pulse and imaging acquisition, is a suitable combination to eliminate potential image artifacts when using the combined TMS-fMRI technique in 3-T MRI scanners.
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